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经皮主动脉瓣植入术治疗重度主动脉瓣狭窄和左心室流出道肿块:一例报告

Treatment of severe aortic stenosis and left ventricular outflow tract mass with transcutaneous aortic valve implantation: a case report.

作者信息

Naeim Hesham A, Saeed Waleed, Alharbi Ibraheem, Abuelatta Reda

机构信息

Madina Cardiac Center, Khaled Bin Waleed ST, PO 6176, Madina, Saudi Arabia.

出版信息

Eur Heart J Case Rep. 2019 Oct 24;3(4):1-5. doi: 10.1093/ehjcr/ytz194. eCollection 2019 Dec.

Abstract

BACKGROUND

Percutaneous implantation of aortic valve for severe aortic stenosis (AS) in the presence of pedunculated mobile left ventricular outflow tract (LVOT) mass not reported before. In this case report, we address the feasibility of this procedure.

CASE SUMMARY

An 80-year-old patient who presented with presyncope, transthoracic echocardiogram (TTE), and transoesophageal echocardiography (TOE) revealed severe calcific AS and LVOT mass measuring 2.1*1.5 cm. The patient was turned down for surgery. It was decided that transcatheter aortic valve implantation (TAVI) be performed because the valve compresses the mass against the proximal part of the interventricular septum. The mass peduncle was 1.4 cm, and it was 4 mm away from the annulus. This meant the valve was needed to be deployed 18 mm below the annulus to cover the mass completely. Gentle manipulation and direct valve deployment without preballoon dilation to decrease the possibility of fragment embolization were necessary. Self-expandable core valve deployed as low as possible, after initial deployment, the distance of LVOT covered by the valve measured by TOE 1.66 cm, the whole mass was covered, then the valve was fully deployed. The patient was extubated in the catheterization room; there was no clinical evidence of embolization. The patient was discharged home after 2 days. A follow-up TTE after 6 months showed a well-functioning valve and the LVOT mass then disappeared.

DISCUSSION

Pedunculated LVOT mass should be resected surgically. In high-risk surgical patients, direct TAVI to compress the mass is feasible in experienced canters. The safety issues need more research and more cases to judge. Transoesophageal echocardiography during the procedure is mandatory to guide the valve position.

摘要

背景

经皮主动脉瓣植入术用于治疗严重主动脉瓣狭窄(AS)且合并有带蒂可移动左心室流出道(LVOT)肿物的情况此前未见报道。在本病例报告中,我们探讨了该手术的可行性。

病例摘要

一名80岁患者,出现前驱晕厥症状,经胸超声心动图(TTE)和经食管超声心动图(TOE)检查显示为严重钙化性AS以及大小为2.1×1.5 cm的LVOT肿物。该患者被拒绝进行手术治疗。鉴于瓣膜可将肿物压向室间隔近端,决定行经导管主动脉瓣植入术(TAVI)。肿物蒂部为1.4 cm,距离瓣环4 mm。这意味着需要将瓣膜置于瓣环下方18 mm处才能完全覆盖肿物。需要轻柔操作并直接植入瓣膜,无需预扩张球囊以降低碎片栓塞的可能性。尽可能低位部署自膨胀式核心瓣膜,初始部署后,经TOE测量瓣膜覆盖的LVOT距离为1.66 cm,整个肿物被覆盖,随后瓣膜完全展开。患者在导管室拔除气管插管;无栓塞的临床证据。2天后患者出院回家。6个月后的随访TTE显示瓣膜功能良好,LVOT肿物消失。

讨论

带蒂LVOT肿物应手术切除。对于手术高危患者,在经验丰富的中心,直接进行TAVI以压迫肿物是可行的。安全问题需要更多研究和更多病例来判断。术中必须进行经食管超声心动图检查以指导瓣膜定位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0e/7042132/2437a910bb91/ytz194f1.jpg

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