Endo Nana, Otsuki Hisao, Domoto Satoru, Yamaguchi Junichi
Department of Cardiology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan.
Department of Cardiovascular Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan.
Eur Heart J Case Rep. 2021 Jan 12;5(2):ytaa565. doi: 10.1093/ehjcr/ytaa565. eCollection 2021 Feb.
Dynamic intraventricular obstruction after transcatheter aortic valve implantation (TAVI) has been previously reported. There is a risk of haemodynamic collapse in the case of left ventricular outflow tract (LVOT) obstruction due to systolic anterior motion (SAM) of the mitral valve.
An 83-year-old woman with aortic stenosis (AS) was referred to our hospital for TAVI. Transthoracic echocardiography revealed a severely calcified aortic valve with a peak velocity of 6.3 m/s across the valve. Acceleration of blood flow (peak velocity 2.6 m/s) at the LVOT due to a septal bulge was also seen. Transfemoral TAVI was performed, and a 29 mm Evolut PRO was implanted under general anaesthesia. After the implantation, a complete atrioventricular block with junctional rhythm developed, and refractory hypotension occurred immediately. Transoesophageal echocardiography revealed LVOT obstruction due to SAM of the mitral valve associated with severe mitral regurgitation (MR), which was not observed preoperatively. Fluid infusion and catecholamine administration were not effective. However, after performing temporary pacing from the right ventricular (RV) apex, the LVOT obstruction and severe MR improved. Her haemodynamics stabilized, and we could complete the procedure. A dual-chamber permanent pacemaker with beta-blocker administration as a longer-term treatment further improved the LVOT obstruction. The patient was finally discharged to a rehabilitation hospital.
Alertness and recognition of potential LVOT obstruction after TAVI are important. Pacing from the RV apex, as well as dual-chamber pacing, comprise a less invasive and feasible therapeutic option in such cases.
经导管主动脉瓣植入术(TAVI)后动态性心室梗阻此前已有报道。二尖瓣收缩期前向运动(SAM)导致左心室流出道(LVOT)梗阻时存在血流动力学崩溃的风险。
一名83岁主动脉瓣狭窄(AS)女性因TAVI转诊至我院。经胸超声心动图显示主动脉瓣严重钙化,瓣膜峰值流速为6.3米/秒。还可见因室间隔膨出导致LVOT血流加速(峰值流速2.6米/秒)。在全身麻醉下进行经股动脉TAVI,并植入一枚29毫米的Evolut PRO瓣膜。植入后,出现完全性房室传导阻滞伴交界性心律,且立即发生难治性低血压。经食管超声心动图显示因二尖瓣SAM导致LVOT梗阻,并伴有严重二尖瓣反流(MR),术前未观察到这种情况。液体输注和儿茶酚胺给药均无效。然而,在右心室(RV)心尖进行临时起搏后,LVOT梗阻和严重MR有所改善。她的血流动力学稳定,我们得以完成手术。作为长期治疗,使用β受体阻滞剂并植入双腔永久起搏器进一步改善了LVOT梗阻。患者最终出院前往康复医院。
TAVI后对潜在LVOT梗阻保持警惕并予以识别很重要。在这种情况下,RV心尖起搏以及双腔起搏是侵入性较小且可行的治疗选择。