Allam Magdy Mohamed, El-Zawawy Hanaa Tarek, Barakat Sherine Samir, Ahmed Soha Magdy, Saleh Rasha Noureldin M
Internal Medicine Department, Endocrinology Unit Alexandria University Student Hospital (AUSH) Alexandria Egypt.
Internal Medicine Department Faculty of Medicine Alexandria University Alexandria Egypt.
Clin Case Rep. 2020 Jan 14;8(2):374-378. doi: 10.1002/ccr3.2654. eCollection 2020 Feb.
Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists after optimizing thyroid function.
亚甲基四氢叶酸还原酶(MTHFR)基因突变可能是甲状腺功能减退患者不孕的原因。因此,如果在优化甲状腺功能后仍存在不孕问题,对不孕的甲状腺功能减退女性及其伴侣进行MTHFR基因突变筛查是值得的。