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三型自身免疫性多腺体综合征（APS III）缓解的诱导：一种具有新前景的老药物。

Induction of remission in autoimmune polyglandular syndrome type three (APS III): An old drug with new perspectives.

作者信息

Allam Magdy Mohamed, Elzawawy Hanaa Tarek Hussein

机构信息

Internal Medicine Department Alexandria University Student Hospital (AUSH) Alexandria Egypt.

Internal Medicine Department, Faculty of Medicine Alexandria University Alexandria Egypt.

出版信息

Clin Case Rep. 2018 Oct 2;6(11):2178-2184. doi: 10.1002/ccr3.1827. eCollection 2018 Nov.

DOI:10.1002/ccr3.1827
PMID:30455916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6230650/
Abstract

The autoimmune polyglandular syndrome is a sequential chain of autoimmune events. Whenever diagnosed, the clinician's target should be induction of remission and if possible hindering its progression especially if associated with refractory vitiligo, resistant Grave's, or unexplained hyperglycemia in T1DM. Azathioprine could be used for induction of remission in autoimmune polyglandular syndrome type three especially with vitiligo and autoimmune thyroiditis.

摘要

自身免疫性多腺体综合征是一系列自身免疫事件。一旦确诊，临床医生的目标应是诱导缓解，若可能应阻止其进展，尤其是在与难治性白癜风、耐药性格雷夫斯病或1型糖尿病中无法解释的高血糖相关时。硫唑嘌呤可用于诱导三型自身免疫性多腺体综合征缓解，尤其是伴有白癜风和自身免疫性甲状腺炎时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4455/6230650/93e9e120c92a/CCR3-6-2178-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4455/6230650/d5c79c906b48/CCR3-6-2178-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4455/6230650/a35559fdd82e/CCR3-6-2178-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4455/6230650/93e9e120c92a/CCR3-6-2178-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4455/6230650/d5c79c906b48/CCR3-6-2178-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4455/6230650/a35559fdd82e/CCR3-6-2178-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4455/6230650/93e9e120c92a/CCR3-6-2178-g003.jpg

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本文引用的文献

1
Polyglandular autoimmune syndromes.自身免疫性多腺体综合征。
J Endocrinol Invest. 2018 Jan;41(1):91-98. doi: 10.1007/s40618-017-0740-9. Epub 2017 Aug 17.
2
Is thyroid autoimmunity itself associated with psychological well-being in euthyroid Hashimoto's thyroiditis?甲状腺自身免疫性与甲状腺功能正常的桥本甲状腺炎患者的心理健康状况本身是否相关？
Endocr J. 2017 Apr 29;64(4):425-429. doi: 10.1507/endocrj.EJ16-0418. Epub 2017 Mar 4.
3
2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum.
甲状腺功能减退患者不孕的一个潜在原因。
Clin Case Rep. 2020 Jan 14;8(2):374-378. doi: 10.1002/ccr3.2654. eCollection 2020 Feb.
4
Improving Hashimoto's thyroiditis by eradicating : Relation to IL-17.通过根除改善桥本甲状腺炎：与白细胞介素-17的关系
Ther Adv Endocrinol Metab. 2020 Feb 21;11:2042018820907013. doi: 10.1177/2042018820907013. eCollection 2020.
5
Autoimmune polyglandular syndrome type III associated with antineutrophil cytoplasmic autoantibody-mediated crescentic glomerulonephritis: A case report and literature review.与抗中性粒细胞胞浆自身抗体介导的新月体性肾小球肾炎相关的Ⅲ型自身免疫性多腺体综合征：病例报告及文献复习
Medicine (Baltimore). 2020 Feb;99(7):e19179. doi: 10.1097/MD.0000000000019179.
美国甲状腺协会2017年妊娠期及产后甲状腺疾病诊断和管理指南。
Thyroid. 2017 Mar;27(3):315-389. doi: 10.1089/thy.2016.0457.
4
Experts Opinion on the Practical Use of Azathioprine and 6-Mercaptopurine in Inflammatory Bowel Disease.硫唑嘌呤和6-巯基嘌呤在炎症性肠病中的实际应用专家意见
Inflamm Bowel Dis. 2016 Nov;22(11):2733-2747. doi: 10.1097/MIB.0000000000000923.
5
An autoimmune polyglandular syndrome complicated with celiac disease and autoimmune hepatitis.一种合并乳糜泻和自身免疫性肝炎的自身免疫性多腺体综合征。
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6
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7
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10
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