Department of Chemistry, Life Sciences and Environmental Sustainability and INSTM UdR Parma University of Parma Parco Area delle Scienze 17/A Parma 43124 Italy.
ChemistryOpen. 2020 Feb 26;9(2):261-268. doi: 10.1002/open.201900345. eCollection 2020 Feb.
The eligibility of tetraquinoxaline cavitands (QxCav) as molecular grippers relies on their unique conformational mobility between a closed () and an open () form, triggered in solution by conventional stimuli like pH, temperature and ion concentration. In the present paper, the mechanochemical conformational switching of functionalized QxCav covalently embedded in an elastomeric polydimethylsiloxane and in a more rigid polyurethane matrix is investigated. The rigid polymer matrix is more effective in converting mechanical force into a conformational switch at the molecular level, provided that all four quinoxaline wings are covalently connected to the polymer.
四氢喹喔啉穴醚（QxCav）作为分子夹的资格取决于它们在封闭（）和开放（）形式之间独特的构象迁移能力，这种构象迁移能力在溶液中由传统刺激如 pH 值、温度和离子浓度触发。在本文中，研究了功能化 QxCav 在弹性聚二甲基硅氧烷和更刚性的聚氨酯基质中的机械化学构象开关。刚性聚合物基质在将机械力转化为分子水平的构象开关方面更有效，前提是所有四个喹喔啉翼都与聚合物共价连接。
