Ngatchou Nadine, Martin Pierre-Yves, Fakhouri Fadi, Pruijm Menno
Service de néphrologie et d'hypertension, CHUV et Université de Lausanne, 1011 Lausanne.
Service de néphrologie, HUG, 1211 Genève 14.
Rev Med Suisse. 2020 Feb 26;16(683):412-416.
Over the last decades, an increasing number of cases of chronic and end-stage kidney disease has been observed in Central America and Asia. This kidney disease mainly affects young farmers without classic renal risk factors. The clinical presentation includes a progressive decrease of the glomerular filtration rate, minimal proteinuria and the presence of tubulo-interstitial nephritis at renal biopsy. A close link with global warming is suspected for this disease, called (according to its location) meso-american nephropathy, Sri Lanka nephropathy or chronic kidney disease of unknown etiology. Others have suggested that intake of water contaminated with pesticides may be responsible. This article provides an overview of this new kidney disease. Measures to prevent acute kidney injury during heat waves in Switzerland are also discussed.
在过去几十年中，中美洲和亚洲慢性及终末期肾病的病例数不断增加。这种肾病主要影响没有典型肾脏危险因素的年轻农民。临床表现包括肾小球滤过率逐渐下降、微量蛋白尿以及肾活检显示存在肾小管间质性肾炎。人们怀疑这种疾病（根据其发生地点被称为中美洲肾病、斯里兰卡肾病或病因不明的慢性肾病）与全球变暖密切相关。也有人认为摄入受农药污染的水可能是病因。本文概述了这种新型肾病。还讨论了瑞士在热浪期间预防急性肾损伤的措施。
