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[慢性阻塞性肺疾病中呼吸功能指标的动态变化]

[Dynamic changes in the functional respiratory indices in chronic obstructive lung disease].

作者信息

Marinov Kh, Dimitrov D, Shoshkov P, Petrova D, Georgiev O

出版信息

Vutr Boles. 1988;27(4):33-6.

PMID:3213022
Abstract

The basic functional respiratory indices were followed up in 50 patients suffering from various forms of chronic obstructive pulmonary disease before and after treatment. A decrease of the dynamic indices followed up was found: inspiration indices--FEV 1% (forced expiratory volume), FVC% (forced vital capacity), FEV 1/FVC%, FEV 1/VC%; flow indices--MEF 25% (maximal expiratory flow), MEF 50% MEF 75%, PEF% (peak expiratory flow), MEF/FVC%, MMEF 25-70% (maximal mean expiratory flow). A decrease of vital capacity and of diffusion capacity was also found. The ratio RV/TLC% (residual volume/total lung capacity) was increased and a general hyperventilation was established. Moderate hypoxemia and lowered saturation by normocapnia and normal pH were also established. The control examinations after treatment showed improvement of all indices followed up.

摘要

对50例患有各种形式慢性阻塞性肺疾病的患者在治疗前后随访了基本的呼吸功能指标。发现随访的动态指标有所下降:吸气指标——FEV 1%(用力呼气量)、FVC%(用力肺活量)、FEV 1/FVC%、FEV 1/VC%;流量指标——MEF 25%(最大呼气流量)、MEF 50%、MEF 75%、PEF%(呼气峰值流量)、MEF/FVC%、MMEF 25 - 70%(最大平均呼气流量)。还发现肺活量和弥散量下降。RV/TLC%(残气量/肺总量)比值升高,并出现了全身性通气过度。还确定存在中度低氧血症,且在正常碳酸血症和正常pH值情况下饱和度降低。治疗后的对照检查显示所有随访指标均有改善。

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