Faculty of Health Sciences, University of Buea, Buea, Cameroon.
Clinical Research Education, Networking & Consultancy (CRENC), Douala, Cameroon.
PLoS One. 2020 Mar 4;15(3):e0229307. doi: 10.1371/journal.pone.0229307. eCollection 2020.
More than 80% of premature deaths due to cardiovascular disease (CVD) occur in low- and middle-income countries. However, access to, and affordability of medications remain a challenge in these countries.
To assess the availability, cost and affordability of essential cardiovascular medicines in the South West region of Cameroon.
In an audit of 63 medicine outlets, twenty-six essential medicines were surveyed using the World Health Organisation (WHO) /Health Action International methodology. Availability, costs and the ratio of the median price to the international reference price were evaluated in public, confessional, private facility medicine outlets, and community pharmacies. Affordability was assessed by calculating the number of days' wages it will cost the lowest-paid unskilled government worker to purchase a month worth of chronic treatment.
Availability ranged from 25.3% (public facility outlets) to 49.2% (community pharmacies) for all medicines. This was higher in urban and semi-urban compared to rural outlets. Cost of medicines was highest in community pharmacies and lowest in public facility outlets. Aspirin, digoxin, furosemide, hydrochlorothiazide and nifedipine were affordable (cost a day's wage or less). Medicines for heart failure and dyslipidaemia (beta blockers, angiotensin converting enzyme inhibitors and statins) required 2-5 days and 6-13 days wages respectively for one month of chronic treatment.
Overall availability of CVD essential medicines was lower than WHO recommendations, and medicines were largely unaffordable. While primary prevention is pivotal, improving availability and affordability of medicines especially for public facilities would provide additional benefit in curbing the CVD burden.
超过 80%的心血管疾病(CVD)导致的过早死亡发生在中低收入国家。然而,这些国家在获得药物和药物负担能力方面仍然面临挑战。
评估喀麦隆西南部地区基本心血管药物的可及性、成本和负担能力。
在对 63 家药品销售点进行审计时,采用世界卫生组织(WHO)/国际健康行动组织的方法对 26 种基本药物进行了调查。评估了公共、宗教、私人医疗机构药品销售点和社区药店的供应情况、成本以及中位数价格与国际参考价格的比率。通过计算出最低工资的非熟练工人购买一个月慢性病治疗所需药物的工资天数来评估可负担性。
所有药物的供应情况从 25.3%(公共医疗机构)到 49.2%(社区药店)不等。城市和半城市地区的供应情况高于农村地区。药店的药品成本最高,公共医疗机构的药品成本最低。阿司匹林、地高辛、呋塞米、氢氯噻嗪和硝苯地平的价格可负担(每天的工资或以下)。用于心力衰竭和血脂异常的药物(β受体阻滞剂、血管紧张素转换酶抑制剂和他汀类药物)分别需要 2-5 天和 6-13 天的工资才能购买一个月的慢性治疗药物。
CVD 基本药物的总体供应情况低于世卫组织的建议,而且药物大多负担不起。虽然初级预防至关重要,但改善药物的可及性和可负担性,特别是对公共设施而言,将在遏制 CVD 负担方面提供额外的益处。