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当失神发作并非癫痫发作时:一例胰岛素瘤病例

When Absence Seizures Are Not Seizure: A Case of Insulinoma.

作者信息

Gowda Smitha Narayana, Abdullah Hafez Mohammad, Sethi Prince, Cunningham Arwyn, Askeland Ryan, Oliver Tony

机构信息

Internal Medicine Residency Program, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

Pathology Residency Program, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

出版信息

S D Med. 2019 Dec;72(12):552-555.

PMID:32130799
Abstract

Insulinomas are rare neuroendocrine tumors that produce excessive insulin and result in hypoglycemia. It can have a wide spectrum of symptoms and presentations which makes it difficult to diagnose at times. Here we present a 39-year-old woman who presented with intermittent diplopia, confusion, and staring episodes for one month. She had previously been seen by a neurologist who diagnosed her with possible absence seizures. However, evaluation showed that that patient had severe hypoglycaemia even with dextrose infusions. She was diagnosed with insulinoma based on lab work and a biopsy of a pancreatic tail mass. She underwent partial pancreatectomy, and has had a good outcome, with no recurrence of her symptoms. This case highlights the variable presentation of insulinomas, and the challenges faced with its diagnosis.

摘要

胰岛素瘤是一种罕见的神经内分泌肿瘤,可分泌过多胰岛素并导致低血糖。其症状和表现多种多样,有时难以诊断。在此,我们报告一名39岁女性,她出现间歇性复视、意识模糊和凝视发作1个月。她之前看过神经科医生,被诊断可能患有失神发作。然而,检查发现即使输注葡萄糖,该患者仍有严重低血糖。根据实验室检查结果和胰腺尾部肿块活检,她被诊断为胰岛素瘤。她接受了胰腺部分切除术,术后恢复良好,症状未复发。本病例突出了胰岛素瘤表现的多样性及其诊断面临的挑战。

相似文献

1
When Absence Seizures Are Not Seizure: A Case of Insulinoma.当失神发作并非癫痫发作时:一例胰岛素瘤病例
S D Med. 2019 Dec;72(12):552-555.
2
Insulinoma as a cause of seizure-like activity and spontaneous hypoglycaemia.胰岛素瘤作为癫痫样活动和自发性低血糖的病因。
BMJ Case Rep. 2023 Jan 10;16(1):e250799. doi: 10.1136/bcr-2022-250799.
3
Insulinoma as a Potential Insidious Presenter in Medical Refractory Epilepsy.胰岛素瘤在药物难治性癫痫中的隐匿性表现
Neuro Endocrinol Lett. 2020 Apr;41(1):46-52.
4
A rare case of insulinoma presenting with postprandial hypoglycemia.一例罕见的胰岛素瘤伴餐后低血糖病例。
Am J Case Rep. 2014 Nov 9;15:488-91. doi: 10.12659/AJCR.891336.
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Re-occurrence of pancreatic insulinoma: an usual cause of hypoglycaemia.胰腺胰岛素瘤复发:低血糖的常见原因。
BMJ Case Rep. 2013 Feb 1;2013:bcr2012008287. doi: 10.1136/bcr-2012-008287.
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[Insulinoma presenting as seizure: case report].[胰岛素瘤表现为癫痫发作:病例报告]
Arq Neuropsiquiatr. 2005 Sep;63(3A):685-8. doi: 10.1590/s0004-282x2005000400026. Epub 2005 Sep 9.
7
[Recurrent seizures of unknown aetiology].
Dtsch Med Wochenschr. 2016 Apr;141(9):631-3. doi: 10.1055/s-0041-103982. Epub 2016 Apr 28.
8
The surgical management of insulinoma.胰岛素瘤的外科治疗
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[A case of glucose-sensitive insulinoma accompanied by slightly elevated serum insulin levels and persisting convulsions after the surgically removed neuroendocrine tumor].
Orv Hetil. 2013 Jan 13;154(2):69-73. doi: 10.1556/OH.2013.29522.
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Seizures Due to Insulinoma- A Rare but Treatable Cause.胰岛素瘤所致癫痫发作——一种罕见但可治疗的病因
J Assoc Physicians India. 2017 Mar;65(3):104-105.