肾细胞癌的手术选择和手术并发症。

Choice of Surgical Options in Kidney Cancer and Surgical Complications.

机构信息

Department of Urology, The Warren Alpert Medical School of Brown University, Providence, RI.

出版信息

Semin Nephrol. 2020 Jan;40(1):42-48. doi: 10.1016/j.semnephrol.2019.12.005.

DOI:10.1016/j.semnephrol.2019.12.005

Abstract

Surgical resection of renal cell carcinoma plays a large role in the overall management of the disease. The gold standard for surgical management historically has been open or laparoscopic radical nephrectomy, however, evidence of equivalent oncologic efficacy with improved clinical outcomes has driven the use of nephron-sparing surgeries, especially for smaller and localized renal tumors. A role for surgery remains in metastatic RCC as well, but controversy exists as to which patients may benefit most from surgical intervention in addition to other systemic targeted therapies. This article focuses specifically on renal cell carcinoma, transitional cell carcinoma is not described here.

摘要

手术切除肾细胞癌在疾病的整体治疗中起着重要作用。手术管理的金标准历来是开放性或腹腔镜根治性肾切除术，但是，具有改善临床结局的等效肿瘤学疗效的证据推动了保肾手术的应用，尤其是对于较小和局限性的肾肿瘤。手术在转移性肾细胞癌中也仍然有作用，但是除了其他全身靶向治疗之外，哪些患者可能从手术干预中获益最多，这仍然存在争议。本文专门针对肾细胞癌，未在此处描述移行细胞癌。