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资源受限环境中的生物阻抗变化检测方法。

Methods for Detection of Bioimpedance Variations in Resource Constrained Environments.

机构信息

Thomas Johann Seebeck Department of Electronics, Tallinn University of Technology, 12616 Tallinn, Estonia.

出版信息

Sensors (Basel). 2020 Mar 2;20(5):1363. doi: 10.3390/s20051363.

DOI:10.3390/s20051363
PMID:32131467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7085632/
Abstract

Changes in a certain parameter are often a few magnitudes smaller than the base value of the parameter, specifying significant requirements for the dynamic range and noise levels of the measurement system. In case of electrical bioimpedance acquisition, the variations can be 1000 times smaller than the entire measured value. Synchronous or lock-in measurement of these variations is discussed in the current paper, and novel measurement solutions are presented. Proposed methods are simple and robust when compared to other applicable solutions. A common feature shared by all members of the group of the proposed solutions is differentiation. It is achieved by calculating the differences between synchronously acquired consecutive samples, with lock-in integration and analog differentiation. All these methods enable inherent separation of variations from the static component of the signal. The variable component of the bioimpedance can, thus, be acquired using the full available dynamic range of the apparatus for its detection. Additive disturbing signals and omnipresent wideband noise are considered and the method for their reduction is proposed.

摘要

某些参数的变化往往比参数的基准值小几个数量级,这对测量系统的动态范围和噪声水平提出了重大要求。在电生物阻抗采集的情况下,变化可能比整个测量值小 1000 倍。本文讨论了这些变化的同步或锁定测量,并提出了新的测量解决方案。与其他适用的解决方案相比,所提出的方法简单且稳健。所提出解决方案组的所有成员共有的一个共同特征是微分。它通过计算同步采集的连续样本之间的差异来实现,具有锁定积分和模拟微分。所有这些方法都能够实现固有变化与信号静态分量的分离。因此,可以使用仪器的全部可用动态范围来检测生物阻抗的可变分量。考虑到附加的干扰信号和无处不在的宽带噪声,并提出了减少它们的方法。

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A Robust Bioimpedance Structure for Smartwatch-Based Blood Pressure Monitoring.基于智能手表的血压监测的稳健生物阻抗结构。
Sensors (Basel). 2018 Jun 29;18(7):2095. doi: 10.3390/s18072095.
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Noninvasive monitoring of blood pressure using optical Ballistocardiography and Photoplethysmograph approaches.使用光学心冲击图和光电容积脉搏波描记法进行无创血压监测。
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:2425-8. doi: 10.1109/EMBC.2013.6610029.
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Non-invasive monitoring of central blood pressure by electrical impedance tomography: first experimental evidence.
采用电阻抗断层成像技术无创监测中心血压:初步实验证据。
Med Biol Eng Comput. 2011 Apr;49(4):409-15. doi: 10.1007/s11517-011-0753-z. Epub 2011 Mar 15.
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Noninvasive measurement of central vascular pressures with arterial tonometry: clinical revival of the pulse pressure waveform?经动脉张力测量法无创测量中心血管压力:脉搏波形态的临床再现?
Mayo Clin Proc. 2010 May;85(5):460-72. doi: 10.4065/mcp.2009.0336.
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Phase angle from bioelectrical impedance analysis: population reference values by age, sex, and body mass index.生物电阻抗分析得出的相位角:按年龄、性别和体重指数划分的人群参考值
JPEN J Parenter Enteral Nutr. 2006 Jul-Aug;30(4):309-16. doi: 10.1177/0148607106030004309.
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Am J Phys Anthropol. 2003 Dec;122(4):361-70. doi: 10.1002/ajpa.10301.
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IEEE Trans Biomed Eng. 1986 Jun;33(6):617-25. doi: 10.1109/TBME.1986.325843.