Sakuranaka Haruyasu, Sekine Akimasa, Miyamoto Ippei, Yamakawa Yuji, Hirata Akifumi, Hagiwara Eri, Igei Koumei, Okamoto Naoki, Ichioka Masahiko
Respiratory Medicine, Tokyo Metropolitan Toshima Hospital, Japan.
Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Intern Med. 2020 Jun 1;59(11):1423-1426. doi: 10.2169/internalmedicine.3716-19. Epub 2020 Mar 5.
A 78-year-old man with a history of surgical resection for ameloblastoma 31 years earlier visited our hospital for prolonged cough. Chest computed tomography showed multiple nodules in both lungs. Although there was no local recurrence in the mandible, the specimen taken from a transbronchoscopic bronchial biopsy showed recurrent ameloblastoma. Despite receiving no treatment, the disease in our patient remained clinically stable for 8.4 years. Chest physicians should be aware that pulmonary malignant ameloblastoma can first relapse several decades after curative surgery. In addition, pulmonary malignant ameloblastoma without local recurrence may be associated with a good prognosis.
一名78岁男性,31年前因成釉细胞瘤接受手术切除,因长期咳嗽前来我院就诊。胸部计算机断层扫描显示双肺有多个结节。尽管下颌骨没有局部复发,但经支气管镜肺活检获取的标本显示为复发性成釉细胞瘤。尽管未接受治疗,但该患者的病情在临床上保持稳定达8.4年。胸科医生应意识到,肺恶性成釉细胞瘤可在根治性手术后数十年首次复发。此外,无局部复发的肺恶性成釉细胞瘤可能预后良好。