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原发性切除术后31年无局部复发的肺恶性成釉细胞瘤：病例报告及文献复习

Pulmonary Malignant Ameloblastoma without Local Recurrence 31 Years after Primary Resection: A Case Report and Literature Review.

作者信息

Sakuranaka Haruyasu, Sekine Akimasa, Miyamoto Ippei, Yamakawa Yuji, Hirata Akifumi, Hagiwara Eri, Igei Koumei, Okamoto Naoki, Ichioka Masahiko

机构信息

Respiratory Medicine, Tokyo Metropolitan Toshima Hospital, Japan.

Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.

出版信息

Intern Med. 2020 Jun 1;59(11):1423-1426. doi: 10.2169/internalmedicine.3716-19. Epub 2020 Mar 5.

DOI:10.2169/internalmedicine.3716-19
PMID:32132332
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7332631/
Abstract

A 78-year-old man with a history of surgical resection for ameloblastoma 31 years earlier visited our hospital for prolonged cough. Chest computed tomography showed multiple nodules in both lungs. Although there was no local recurrence in the mandible, the specimen taken from a transbronchoscopic bronchial biopsy showed recurrent ameloblastoma. Despite receiving no treatment, the disease in our patient remained clinically stable for 8.4 years. Chest physicians should be aware that pulmonary malignant ameloblastoma can first relapse several decades after curative surgery. In addition, pulmonary malignant ameloblastoma without local recurrence may be associated with a good prognosis.

摘要

一名78岁男性，31年前因成釉细胞瘤接受手术切除，因长期咳嗽前来我院就诊。胸部计算机断层扫描显示双肺有多个结节。尽管下颌骨没有局部复发，但经支气管镜肺活检获取的标本显示为复发性成釉细胞瘤。尽管未接受治疗，但该患者的病情在临床上保持稳定达8.4年。胸科医生应意识到，肺恶性成釉细胞瘤可在根治性手术后数十年首次复发。此外，无局部复发的肺恶性成釉细胞瘤可能预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/a2ab1d44bf55/1349-7235-59-1423-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/f0914291d381/1349-7235-59-1423-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/b207b132fb2b/1349-7235-59-1423-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/627d16f46216/1349-7235-59-1423-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/a2ab1d44bf55/1349-7235-59-1423-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/f0914291d381/1349-7235-59-1423-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/b207b132fb2b/1349-7235-59-1423-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/627d16f46216/1349-7235-59-1423-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b28/7332631/a2ab1d44bf55/1349-7235-59-1423-g004.jpg

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本文引用的文献

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Malignant ameloblastoma (metastatic ameloblastoma) in the lung: 3 cases of misdiagnosis as primary lung tumor with a unique growth pattern.肺内恶性成釉细胞瘤（转移性成釉细胞瘤）：3例误诊为原发性肺肿瘤并具有独特生长模式。
Diagn Pathol. 2015 Jul 25;10:123. doi: 10.1186/s13000-015-0367-0.
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Metastatic pulmonary ameloblastoma misdiagnosed as primary squamous cell carcinoma preoperatively.术前被误诊为原发性鳞状细胞癌的转移性肺成釉细胞瘤。
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一例复发性转移性成釉细胞瘤合并高钙血症经卡铂和紫杉醇成功治疗：长期生存及疾病长期稳定
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Malignant ameloblastoma metastatic to the lungs 29 years after primary resection: a case report.原发性切除术后29年发生肺转移的恶性成釉细胞瘤：1例报告
Chest. 2002 Apr;121(4):1359-61. doi: 10.1378/chest.121.4.1359.
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Pulmonary metastasis of ameloblastoma: case report and review of the literature.成釉细胞瘤的肺转移：病例报告及文献复习
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999 Aug;88(2):170-6. doi: 10.1016/s1079-2104(99)70113-7.
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Nihon Naika Gakkai Zasshi. 1998 Jul 10;87(7):1376-8.