Bernasowski A, Kunze M, Bernasowski A, Metzel D
Klinik für Innere Medizin des Bezirkskrankenhauses, Suhl.
Zentralbl Chir. 1988;113(21):1388-92.
Bile was collected intraoperatively and through duodenal tubes from patients and was microbiologically investigated. E. coli and coliform bacteria were found to be the most common germs in bile, accounting for 51.6 per cent of all positive findings. Streptococcus faecalis and Proteus spec. increased remarkably to 17 per cent each. Calculated antibiotic therapy was found to depend for good success on knowledge of the latest resistance rates of the most common germs. These were 67 per cent E. coli to ampicillin and 40 per cent for E. coli to tetracycline and 53 or 91 per cent for Str. faecalis or Proteus spec. to tetracycline. Hence, these preparations will have to be abandoned for calculated therapy, say, for cholangitis.
术中从患者体内收集胆汁，并通过十二指肠管收集胆汁，进行微生物学研究。发现大肠杆菌和大肠菌群是胆汁中最常见的细菌，占所有阳性结果的51.6%。粪链球菌和变形杆菌属显著增加至各占17%。发现精确的抗生素治疗要想取得良好效果，取决于对最常见细菌最新耐药率的了解。这些耐药率分别为：大肠杆菌对氨苄西林的耐药率为67%，对四环素的耐药率为40%；粪链球菌或变形杆菌属对四环素的耐药率为53%或91%。因此，对于胆管炎等精确治疗而言，这些制剂将不得不被弃用。
