Dermatology Units and Burn Center Ausl Romagna, Bufalini Hospital, Viale Ghirotti, 286,, 47521, Cesena, Italy.
Dermatology Unit Ausl Romagna, Infermi Hospital, Viale Stradone, 9, 48018, Faenza, Italy.
Int J Biometeorol. 2020 Jul;64(7):1145-1152. doi: 10.1007/s00484-020-01888-y. Epub 2020 Mar 5.
This study assessed the effects of liman peloid, followed by bath and heliotherapy in psoriatic patients at Cervia, Emilia, Italy. The psoriatic patients were randomized into two groups: group 1 with 56 patients, treated with liman applications, bath, and heliotherapy, and group 2 with 35 subjects, treated with mud-bath therapy using a clay peloid mixed with tap water and heliotherapy. Data was collected for the following: psoriasis area and severity index (PASI); delta-PASI (difference between post- and pre-treatment PASI); delta-PASI3 and delta-PASI6, 3 and 6 months after the end of treatment, respectively; psoriasis recurrences; and the use of both topical and systemic drugs. Although not significant, a decrease in PASI was recorded in group 1 at the end of treatment and after 3 and 6 months. Compared with group 2, there was a significant change in delta-PASI, delta-PASI3, and psoriasis recurrences in group 1 as well as a significant reduction in the topical use of drugs, both cortisone and nonsteroid drugs. This is the first and preliminary study which documented the efficacy of a specific protocol of liman bath heliotherapy in psoriatic patients as documented by a reduction in delta-PASI and delta-PASI3, a decrease in psoriasis recurrences, and use of topical drugs.
本研究评估了利曼泥疗，随后在意大利艾米利亚的切尔维亚对银屑病患者进行沐浴和光疗的效果。银屑病患者被随机分为两组：第 1 组 56 例，接受利曼泥敷、沐浴和光疗治疗；第 2 组 35 例，接受含有自来水的粘土泥浴疗法和光疗治疗。收集以下数据：银屑病面积和严重程度指数（PASI）；delta-PASI（治疗前后 PASI 的差异）；delta-PASI3 和 delta-PASI6，分别为治疗结束后 3 个月和 6 个月；银屑病复发；以及局部和全身药物的使用情况。尽管没有统计学意义，但第 1 组在治疗结束时以及治疗后 3 个月和 6 个月时 PASI 均有下降。与第 2 组相比，第 1 组的 delta-PASI、delta-PASI3 和银屑病复发有显著变化，同时局部使用皮质类固醇和非甾体药物也显著减少。这是第一项也是初步研究，记录了特定的利曼浴光疗方案对银屑病患者的疗效，具体表现为 delta-PASI 和 delta-PASI3 的减少、银屑病复发的减少以及局部药物的使用减少。
