Center for Consciousness Science, Neuroscience Graduate Program, and Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Department of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, the Netherlands; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, the Netherlands; Department of Psychiatry, Academic Medical Center, Amsterdam, the Netherlands.
Neuron. 2020 Mar 4;105(5):776-798. doi: 10.1016/j.neuron.2020.01.026.
We review the central tenets and neuroanatomical basis of the global neuronal workspace (GNW) hypothesis, which attempts to account for the main scientific observations regarding the elementary mechanisms of conscious processing in the human brain. The GNW hypothesis proposes that, in the conscious state, a non-linear network ignition associated with recurrent processing amplifies and sustains a neural representation, allowing the corresponding information to be globally accessed by local processors. We examine this hypothesis in light of recent data that contrast brain activity evoked by either conscious or non-conscious contents, as well as during conscious or non-conscious states, particularly general anesthesia. We also discuss the relationship between the intertwined concepts of conscious processing, attention, and working memory.
我们回顾了全局神经元工作空间（GNW）假说的核心原则和神经解剖学基础，该假说试图解释有关人类大脑意识加工基本机制的主要科学观察结果。GNW 假说提出，在意识状态下，与递归处理相关的非线性网络点火会放大和维持神经表示，从而允许本地处理器全局访问相应的信息。我们根据最近的数据来检验这个假说，这些数据对比了意识或非意识内容所引起的大脑活动，以及在意识或非意识状态下，特别是全身麻醉期间的大脑活动。我们还讨论了意识处理、注意力和工作记忆这几个概念之间的相互关系。
