Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.
Paracelsus Medical University of Salzburg, Salzburg, Austria.
Ophthalmic Res. 2020;63(6):572-579. doi: 10.1159/000506953. Epub 2020 Mar 5.
To determine the vascular density of the anterior segment (AS) of the eye from optical coherence tomography angiography (OCTA) images and slit-lamp photographs.
A swept-source OCTA (Plex Elite 9000; Carl Zeiss) device modified with a +10-diopter lens was used to record the vasculature of the AS. Twenty eyes, including 4 eyes of 4 healthy subjects and 16 eyes of 12 patients scheduled for cataract surgery or combined vitrectomy and cataract surgery, were studied. The slit-lamp photographs of the AS were acquired concurrently with the AS-OCTA images. The vascular density was measured preoperatively and postoperatively in the nasal, temporal, superior, and inferior quadrants after binarization with ImageJ software.
Acceptable AS-OCTA images were obtained of 65% (superior), 80% (nasal), 70% (inferior), and 80% (temporal) of the eyes. The percentage of acceptable images was significantly lower in the superior quadrant among the AS-OCTA images than among the AS photographs (100%; p = 0.004). The vascular density determined by AS-OCTA was higher than that determined in the AS photographs in all quadrants (p = 0.011 to <0.001). The AS-OCTA B-mode images showed that vascular flow was identified mainly between the conjunctiva and sclera but not in the ciliary body. The vascular density increased significantly after cataract surgery in the superior quadrant, which was significantly correlated with the location of the surgical incision (p = 0.03).
AS-OCTA can obtain images with higher vascular density of the conjunctiva and sclera than slit-lamp photographs, and AS-OCTA images can show a postoperative increase in vascular density.
从光相干断层扫描血管造影（OCTA）图像和裂隙灯照片确定眼前节（AS）的血管密度。
使用带有+10 屈光度透镜的扫频源 OCTA（Plex Elite 9000；卡尔蔡司）设备记录 AS 的脉管系统。研究了 20 只眼睛，包括 4 名健康受试者的 4 只眼睛和 12 名接受白内障手术或联合玻璃体切除术和白内障手术的患者的 16 只眼睛。同时采集 AS-OCTA 图像和 AS 裂隙灯照片。使用 ImageJ 软件进行二值化后，在术前和术后分别测量鼻侧、颞侧、上侧和下侧象限的血管密度。
可获得 65%（上象限）、80%（鼻侧）、70%（下象限）和 80%（颞侧）的可接受 AS-OCTA 图像。AS-OCTA 图像的上象限可接受图像的百分比明显低于 AS 照片（100%；p = 0.004）。AS-OCTA 确定的血管密度在所有象限均高于 AS 照片（p = 0.011 至 <0.001）。AS-OCTA B 型图像显示，血管血流主要在结膜和巩膜之间识别，但不在睫状体中识别。白内障手术后上象限的血管密度显著增加，与手术切口的位置显著相关（p = 0.03）。
AS-OCTA 可以获得比裂隙灯照片更高的结膜和巩膜血管密度的图像，并且 AS-OCTA 图像可以显示术后血管密度增加。
