College of Sport and Health Science, Ritsumeikan University, Shiga 525-8577, Japan.
National Institute of Advanced Industrial Science and Technology, Chiba 277-0882, Japan.
Int J Environ Res Public Health. 2020 Mar 3;17(5):1620. doi: 10.3390/ijerph17051620.
There is little consensus regarding the impacts of physical activity and nutrient intake on bone mineral density (BMD) in subjects with high or low levels of arterial stiffness. This study was performed to investigate whether physical activity and nutrient intake are associated with BMD in middle-aged women with high levels of arterial stiffness. The study population consisted of middle-aged women aged 40-64 years ( = 22). BMD was assessed by dual-energy X-ray absorptiometry. Carotid-femoral pulse wave velocity (cf-PWV) was used as an indicator of arterial stiffness. Subjects were divided into two groups by median cf-PWV. Physical activity in free-living conditions was evaluated using a triaxial accelerometer. Nutrient intake was also measured using the brief-type self-administered diet history questionnaire. In the High-PWV group, BMD showed a significant negative correlation with age. Using a partial correlation model, BMD was associated with the number of steps and unsaturated fatty acid intake in the High-PWV group. These results suggest that BMD in middle-aged women with high levels of arterial stiffness may be associated with both the number of steps and nutritional intake. Recommendations of physical activity and nutritional intake for the prevention of osteopenia should include consideration of arterial stiffness.
关于动脉僵硬度水平高或低的个体，体力活动和营养摄入对骨密度（BMD）的影响尚未达成共识。本研究旨在探讨体力活动和营养摄入与动脉僵硬度水平高的中年女性的 BMD 是否相关。研究对象为年龄在 40-64 岁的中年女性（n=22）。采用双能 X 射线吸收法评估 BMD。颈动脉-股动脉脉搏波速度（cf-PWV）用作动脉僵硬度的指标。根据 cf-PWV 的中位数将受试者分为两组。采用三轴加速度计评估自由生活条件下的体力活动。使用简短型自我管理饮食史问卷来测量营养素的摄入。在高 PWV 组中，BMD 与年龄呈显著负相关。在部分相关模型中，高 PWV 组的 BMD 与步数和多不饱和脂肪酸摄入呈正相关。这些结果表明，动脉僵硬度水平高的中年女性的 BMD 可能与步数和营养摄入有关。预防骨质疏松症的体力活动和营养摄入建议应考虑到动脉僵硬度。
