Papi Piero, Di Murro Bianca, Tromba Marco, Passarelli Pier Carmine, D'Addona Antonio, Pompa Giorgio
Department of Oral and Maxillo-Facial Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.
Division of Oral Surgery and Implantology, Department of Head and Neck, Oral Surgery, and Implantology Unit, Institute of Clinical Dentistry, Catholic University of Sacred Hearth, Fondazione Policlinico Universitario Gemelli, 00168 Rome, Italy.
Antibiotics (Basel). 2020 Mar 3;9(3):110. doi: 10.3390/antibiotics9030110.
:The aims of this study were to obtain preliminary data and test the clinical efficacy of a novel nonporous dense-polytetrafluoroethylene (d-PTFE) membrane (permamem®, botiss) in alveolar ridge preservation (ARP) procedures with a flapless approach. A traumatic extraction was performed in the premolar maxillary area, and a d-PTFE membrane was used to seal the alveolar cavity: no biomaterial was used to graft the socket and the membrane was left intentionally exposed and stabilized with sutures. The membrane was removed after four weeks and dental implants were placed four months after the procedure. The primary outcome variables were defined as the dimensional changes in the ridge width and height after four months. A total of 15 patients were enrolled in this study. The mean width of the alveolar cavity was 8.9 ± 1.1 mm immediately after tooth extraction, while four months later a mean reduction of 1.75 mm was experienced. A mean vertical reduction of 0.9 ± 0.42 mm on the buccal aspect and 0.6 ± 0.23 mm on the palatal aspect were recorded at implant placement. Within the limitations of this study, the d-PTFE membrane proved to be effective in alveolar ridge preservation, with the outcomes of the regeneration not affected by the complete exposure of this biomaterial.
本研究的目的是获取初步数据,并测试一种新型无孔致密聚四氟乙烯(d-PTFE)膜(permamem®,botiss)在无瓣方法的牙槽嵴保存(ARP)手术中的临床疗效。在上颌前磨牙区进行了一次创伤性拔牙,使用d-PTFE膜封闭牙槽腔:未使用生物材料填充牙槽窝,且故意使膜暴露在外并用缝线固定。四周后取出膜,并在手术后四个月植入牙种植体。主要结局变量定义为四个月后牙槽嵴宽度和高度的尺寸变化。本研究共纳入15例患者。拔牙后即刻牙槽腔的平均宽度为8.9±1.1mm,而四个月后平均减少了1.75mm。在植入种植体时,颊侧平均垂直减少0.9±0.42mm,腭侧平均垂直减少0.6±0.23mm。在本研究的局限性内,d-PTFE膜在牙槽嵴保存方面被证明是有效的,该生物材料的完全暴露并未影响再生结果。