Adrenal spindle-cell sarcoma with features of malignant peripheral nerve sheath tumor.

An unusual malignant spindle-cell tumor of the adrenal medulla originally diagnosed as leiomyosarcoma is illustrated. On the evidence of histological and immunohistochemical findings, the neoplasm was rediagnosed as a spindle-cell sarcoma with features of malignant peripheral nerve sheath tumor. Unlike ordinary pheochromocytoma, which may also show a spindling cell pattern, such lesions are malignant and its recognition may have implications for prognosis and management of patients.