Okhovat A A, Ansari B, Basiri K, Fatehi F
Faculty of Medicine, Tehran University of Medical Sciences, Shariati Hospital, North Kargar Street, Tehran, Iran.
Department of Neurology, Isfahan University of Medical Sciences, Alzahra Hospital, Isfahan, Iran.
Rev Neurol (Paris). 2020 Dec;176(10):856-863. doi: 10.1016/j.neurol.2019.12.004. Epub 2020 Mar 3.
Opium sale is prohibited in Iran, and sellers mix it with lead to increase the weight. Herein, we describe neuromuscular findings in nine patients who developed lead poisoning due to opium/drug consumption. The mean age of patients was 53±3.5 years and their mean blood lead level was 122.6±20.8μg/dL. Most of the patients had an acute/subacute course presenting as axonal or demyelinating sensorimotor polyneuropathy, motor neuron disease, and multiple mononeuropathies with favorable response to the chelation therapy. Lead poisoning should be considered in patients with a history of opium use and neuromuscular symptoms.
伊朗禁止鸦片销售，卖家会将其与铅混合以增加重量。在此，我们描述了9名因吸食鸦片/毒品而发生铅中毒的患者的神经肌肉检查结果。患者的平均年龄为53±3.5岁，平均血铅水平为122.6±20.8μg/dL。大多数患者呈急性/亚急性病程，表现为轴索性或脱髓鞘性感觉运动性多发性神经病、运动神经元病和多发性单神经病，对螯合疗法反应良好。有鸦片使用史且出现神经肌肉症状的患者应考虑铅中毒。
