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射血分数保留的心力衰竭的管理

Management of heart failure with preserved ejection fraction.

作者信息

Gard Emma, Nanayakkara Shane, Kaye David, Gibbs Harry

机构信息

Monash University, Clayton, Vic.

Department of Cardiology, Alfred Health, Melbourne.

出版信息

Aust Prescr. 2020 Feb;43(1):12-17. doi: 10.18773/austprescr.2020.006. Epub 2020 Feb 3.

Abstract

Heart failure with preserved ejection fraction is a highly heterogenous disease. There is emerging evidence that treatment should be tailored to the individual’s associated comorbidities No current algorithms exist for the management of heart failure with preserved ejection fraction. Conventional therapies used in heart failure with reduced ejection fraction are yet to show a mortality benefit Key treatment objectives include control of hypertension and fluid balance Common comorbidities include coronary artery disease, atrial fibrillation, obesity, diabetes, renal impairment and pulmonary hypertension. These comorbidities should be considered in all patients and treatment optimised

摘要

射血分数保留的心力衰竭是一种高度异质性疾病。越来越多的证据表明,治疗应根据个体的合并症进行调整。目前尚无用于管理射血分数保留的心力衰竭的算法。射血分数降低的心力衰竭中使用的传统疗法尚未显示出死亡率获益。主要治疗目标包括控制高血压和液体平衡。常见的合并症包括冠状动脉疾病、心房颤动、肥胖、糖尿病、肾功能损害和肺动脉高压。所有患者都应考虑这些合并症并优化治疗。

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本文引用的文献

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Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction.达格列净治疗射血分数降低的心力衰竭患者。
N Engl J Med. 2019 Nov 21;381(21):1995-2008. doi: 10.1056/NEJMoa1911303. Epub 2019 Sep 19.
3
Heart failure drug treatment.心力衰竭药物治疗。
Lancet. 2019 Mar 9;393(10175):1034-1044. doi: 10.1016/S0140-6736(18)31808-7.

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