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伴有椎旁和胸段脊柱硬膜外受累的罗萨伊-多夫曼病:病例报告及文献综述

Rosai-Dorfman disease with paravertebral and epidural thoracic spine involvement: A case report and literature review.

作者信息

Jayaram Abhilash, Al Maslamani Nasser Jassim, Rahiman Nazeer Ahamad Puthiyaveetil Abdul, Negi Vidya Chander

机构信息

Hamad Medical Corporation, Clinical Imaging, Doha, Qatar.

出版信息

Radiol Case Rep. 2020 Feb 25;15(5):484-488. doi: 10.1016/j.radcr.2020.01.026. eCollection 2020 May.

Abstract

Rosai-Dorfman disease (RDD) with spinal cord involvement is a rare clinical entity. We report a case of RDD with paravertebral and intraspinal epidural involvement in a 24-year-old male Bangladeshi patient who presented with progressive bilateral lower limb weakness for 20 days duration associated with spasticity and muscle spasm. MRI demonstrated an enhancing paravertebral soft tissue lesion extending from C7 through T4 with intraspinal epidural extension encasing the spinal cord with focal cord oedema. Histopathology of the paraspinal-epidural lesion reported a finding consistent with RDD. The patient was initiated on high-dose steroids. Follow up after 2 months demonstrated symptomatic improvement as the patient was able to move on the crutch and repeated MRI showed lesion regression.

摘要

伴有脊髓受累的罗萨伊-多夫曼病(RDD)是一种罕见的临床病症。我们报告一例24岁孟加拉男性患者的RDD病例,该患者出现椎旁和椎管内硬膜外受累,表现为进行性双侧下肢无力20天,伴有痉挛和肌肉痉挛。MRI显示一个强化的椎旁软组织病变,从C7延伸至T4,伴有椎管内硬膜外延伸,包绕脊髓并伴有局灶性脊髓水肿。椎旁-硬膜外病变的组织病理学报告结果与RDD一致。该患者开始接受大剂量类固醇治疗。2个月后的随访显示症状有所改善,患者能够借助拐杖行走,重复MRI显示病变消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f91/7044493/a7b3bd5d1b78/gr1.jpg

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