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Reflections on the History of HCV: A Posthumous Examination.

作者信息

Alter Harvey J, Farci Patrizia, Bukh Jens, Purcell Robert H

机构信息

Department of Transfusion Medicine Clinical Center National Institutes of Health Bethesda MD.

Laboratory of Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD.

出版信息

Clin Liver Dis (Hoboken). 2020 Mar 2;15(Suppl 1):S64-S71. doi: 10.1002/cld.882. eCollection 2020 Feb.

DOI:10.1002/cld.882
PMID:32140215
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7050949/
Abstract
摘要

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Immunoglobulin with High-Titer In Vitro Cross-Neutralizing Hepatitis C Virus Antibodies Passively Protects Chimpanzees from Homologous, but Not Heterologous, Challenge.具有高滴度体外交叉中和丙型肝炎病毒抗体的免疫球蛋白可被动保护黑猩猩免受同源但非异源攻击。
J Virol. 2015 Sep;89(17):9128-32. doi: 10.1128/JVI.01194-15. Epub 2015 Jun 17.
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Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14562-7. doi: 10.1073/pnas.1210592109. Epub 2012 Jul 24.
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In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus.体内评估针对丙型肝炎病毒的多克隆抗体的跨基因型中和活性。
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