Stieglitz S, Heppner H J, Netzer N
Department of Pneumology, Allergy, Sleep and Intensive Care Medicine, Petrus Hospital Wuppertal, Carnaper Str. 48, 42283, Wuppertal, Germany.
University of Witten-Herdecke, Witten-Herdecke, Germany.
Z Gerontol Geriatr. 2020 Mar;53(2):119-122. doi: 10.1007/s00391-020-01714-5. Epub 2020 Mar 5.
Parasomnias are characterized by abnormal experiences, dreams, movements and behavior during sleep. They may occur in the middle of the sleep during REM (rapid eye movement) or NREM (non-rapid eye movement), during falling asleep or waking up. Characteristically for REM behavior disorder is an increased muscle tone although usually REM is defined by an absence of muscle tone. For these forms aggressive dreams may lead to violating bed partners or self-injury of the sleeping person. Even killing bed partners has been described. Many of the patients develop a kind of Parkinson's disease (synucleinopathies). The rate of phenoconversion is more than 30% in 5 years and nearly 100% after 15 years. There are several recommendations regarding a safe sleeping environment. Medicinal treatment consists of either melatonin or clonazepam.
睡眠障碍的特征是睡眠期间出现异常体验、梦境、动作和行为。它们可能发生在快速眼动(REM)睡眠或非快速眼动(NREM)睡眠的中间阶段、入睡或醒来时。快速眼动行为障碍的特征是肌张力增加,尽管通常快速眼动睡眠的定义是肌张力缺失。对于这些形式,攻击性梦境可能导致伤害同床者或睡眠者自我伤害。甚至有杀害同床者的描述。许多患者会发展为某种帕金森病(突触核蛋白病)。5年内症状转化的发生率超过30%,15年后接近100%。关于安全睡眠环境有多项建议。药物治疗包括褪黑素或氯硝西泮。