Wendt S, Ranft D, de With K, Kern W V, Salzberger B, Lübbert C
Bereich Infektions- und Tropenmedizin, Klinik und Poliklinik für Gastroenterologie, Hepatologie, Infektiologie, Pneumologie, Department für Innere Medizin, Neurologie und Dermatologie, Universitätsklinikum Leipzig, AöR, Liebigstr. 20, 04103, Leipzig, Deutschland.
Interdisziplinäres Zentrum für Infektionsmedizin (ZINF), Universitätsklinikum Leipzig, Leipzig, Deutschland.
Internist (Berl). 2020 Apr;61(4):375-387. doi: 10.1007/s00108-020-00762-8.
Against the background of increasing antimicrobial resistance, antibiotic stewardship (ABS) is an important measure to counteract the spread of resistant pathogens and multidrug resistance. For Germany and Austria, a comprehensive S3 guideline is available, which was last updated in 2018. The control of antibiotic or anti-infective use in hospitals should be guided by specialized ABS teams. At the hospital level, ABS also includes a structured ongoing analysis of local antibiotic use and resistance data. Recommendations for locally adapted therapy regimens should be derived and implemented from this data analysis. ABS consists of regular ward rounds ("ABS visits"), during which members of the ABS team review the indication, dosage, route of administration and duration of antimicrobial therapy at the bedside. Here, the key challenge is to save antibiotics without compromising the individual patient. Digitalization and artificial intelligence offer new options for ABS, while the adaption of inpatient concepts to outpatient care is also important.
在抗菌药物耐药性不断增加的背景下，抗生素管理（ABS）是应对耐药病原体传播和多重耐药的一项重要措施。德国和奥地利有一份全面的S3指南，该指南上次更新于2018年。医院抗生素或抗感染药物使用的控制应由专业的抗生素管理团队指导。在医院层面，抗生素管理还包括对当地抗生素使用和耐药数据进行结构化的持续分析。应根据该数据分析得出并实施针对当地情况的治疗方案建议。抗生素管理包括定期的病房巡查（“抗生素管理巡查”），在此期间，抗生素管理团队成员会在床边审查抗菌治疗的适应症、剂量、给药途径和疗程。在这里，关键挑战是在不影响个体患者的情况下节省抗生素。数字化和人工智能为抗生素管理提供了新的选择，同时将住院治疗理念应用于门诊护理也很重要。
