经动脉化疗栓塞治疗阴道癌的临床疗效。

Clinical outcomes of transarterial chemotherapy and embolization for vaginal cancer.

机构信息

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

J Obstet Gynaecol Res. 2020 Jun;46(6):924-930. doi: 10.1111/jog.14234. Epub 2020 Mar 6.

DOI:10.1111/jog.14234

PMID:32144875

Abstract

AIM

We report clinical outcomes of transarterial embolization in 19 cases of vaginal cancer.

METHODS

From August 2011 to October 2019, 19 patients with histologically diagnosed vaginal cancer were identified in our department. Transarterial chemotherapy and embolization was performed for all patients. Patient characteristics, treatment plans and the clinical outcomes, were recorded.

RESULTS

Among 19 identified cases, nine of them are squamous cell carcinoma, five of adenocarcinoma, one of adenosquamous carcinoma, two of vaginal malignant melanoma, one leiomyosarcoma and one of stromal sarcoma. Transarterial chemotherapy and embolization was successfully performed in all patients. No related complication was found after intervention treatment. Besides, eight patients received adjuvant chemotherapy, four received both adjuvant chemotherapy and radiotherapy and seven received no therapies. Four patients were cured and seven were stable during follow-up.

CONCLUSION

Transarterial embolization appears safe and effective for vaginal cancer, with a currently acceptable prognosis.

摘要

目的

我们报告了 19 例阴道癌患者行动脉栓塞治疗的临床结果。

方法

自 2011 年 8 月至 2019 年 10 月，我们科室共确诊了 19 例组织学诊断为阴道癌的患者。所有患者均接受了经动脉化疗栓塞治疗。记录患者的特征、治疗方案和临床结果。

结果

在这 19 例患者中，9 例为鳞状细胞癌，5 例为腺癌，1 例为腺鳞癌，2 例为阴道恶性黑色素瘤，1 例为平滑肌肉瘤，1 例为间质肉瘤。所有患者均成功地进行了经动脉化疗栓塞治疗，干预治疗后未发现相关并发症。此外，8 例患者接受了辅助化疗，4 例患者同时接受了辅助化疗和放疗，7 例患者未接受治疗。随访期间，4 例患者治愈，7 例患者病情稳定。