[Age-related factors in the impact of chemical peeling with retinol on the functional parameters of the skin.].

Retinoids continue to be the main mean for the treatment of photoaging as they are able to align not only the various wrinkles but also to reduce skin pigmentation. Retinol serves as a reserve turned into an active substance by the cell itself in the required amount that triggers the expression of genes responsible for the development of epithelial tissue. The aim of the research therefore was to study the dynamics of the functional parameters of the skin after peeling with retinol in different age groups. 58 patients who had been treating with chemical peeling with retinol were under observation. All the patients were divided into two groups by age: the 1st group - 29 women from 30 to 45 years (38,51±4,34 years), the 2nd group - 29 women from 46 to 60 years (52,97±5,34 years). We studied the moisture content, acid-base balance, pigmentation, erythema degree, skin salinity and elasticity before treatment, 14 and 28 days after peeling. It was found that peeling with retinol bleached the skin better in the patients of the older age group, although their skin was more sensitive to the components of peeling. In the study of elasticity in the older age group, peeling with retinol reduced the extensibility, significantly increased the tone, viscosity and improved the total elasticity of the skin. Chemical peeling with retinol had the best effect on the skin in patients 46-60 years.