Reddy Aarthi S, Uceda Domingo E, Al Najafi Mina, Dey Amit K, Mehta Nehal N
Section of Inflammation and Cardiometabolic Diseases, National Heart, Lung and Blood Institute, Clinical Research Center, 10 Center Drive, Room 5-5140, Bethesda, MD 20892, USA.
Section of Inflammation and Cardiometabolic Diseases, National Heart, Lung and Blood Institute, Clinical Research Center, 10 Center Drive, Room 5-5140, Bethesda, MD 20892, USA.
PET Clin. 2020 Apr;15(2):207-213. doi: 10.1016/j.cpet.2019.11.009.
Fluorodeoxyglucose-PET/computed tomography combines the high sensitivity of PET with the excellent spatial resolution provided by computed tomography, making it a potentially powerful tool for capturing and quantifying early vascular diseases. Patients with chronic inflammatory states have an increased risk of cardiovascular events; there is also increased vascular fluorodeoxyglucose uptake seen compared with healthy controls. This review examines the use of fluorodeoxyglucose-PET/computed tomography in assessing low-grade vascular inflammation in chronic inflammation and then reviews fluorodeoxyglucose-PET/computed tomography as a tool in monitoring the efficacy of various treatments known to modulate cardiovascular disease.
氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（Fluorodeoxyglucose-PET/CT）将PET的高灵敏度与计算机断层扫描提供的出色空间分辨率相结合，使其成为捕捉和量化早期血管疾病的潜在有力工具。患有慢性炎症状态的患者发生心血管事件的风险增加；与健康对照相比，血管内氟脱氧葡萄糖摄取也增加。本综述探讨了氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在评估慢性炎症中低度血管炎症方面的应用，然后回顾了氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描作为监测已知可调节心血管疾病的各种治疗效果的工具的情况。
