Department of Biology, University of Padova, Via U. Bassi, 58/B 35131, Padova, Italy.
Department of Biology, University of Padova, Via U. Bassi, 58/B 35131, Padova, Italy.
Environ Pollut. 2020 Jul;262:114273. doi: 10.1016/j.envpol.2020.114273. Epub 2020 Feb 28.
The pollution of aquatic bodies by pharmaceutical compounds is an emerging environmental problem, with little explored consequences. Oxytetracycline (OTC) is an antibiotic used for treatment of infections caused by a variety of microorganisms and it is widely employed in medicine, livestock husbandry and aquaculture. This pharmaceutical compound may cause deleterious effects on non-target aquatic organisms as microalgae. The objective of this study was to evaluate the effects of OTC on growth, pigment content and morpho-physiology of the microalga Isochrysis galbana Parke. The results highlighted that OTC exposure inhibited the growth of I. galbana in cultures treated with OTC 5.0 and 10.0 mg/L after 3 days and in cultures treated with OTC 5.0, 7.5 and 10.0 mg/L after 5 days. Effects of OTC on cells ultrastructure and physiology consisted in large cytoplasmic lipid inclusions and in a decrease of photosynthetic pigments amount.
水体中药物化合物的污染是一个新出现的环境问题，其后果还在探索之中。土霉素（OTC）是一种用于治疗多种微生物引起的感染的抗生素，广泛应用于医学、畜牧业和水产养殖业。这种药物化合物可能对微藻等非目标水生生物产生有害影响。本研究旨在评估 OTC 对小球藻生长、色素含量和形态生理学的影响。结果表明，OTC 暴露抑制了 5.0 和 10.0 mg/L OTC 处理后 3 天以及 5.0、7.5 和 10.0 mg/L OTC 处理后 5 天的小球藻培养物的生长。OTC 对细胞超微结构和生理学的影响包括细胞质中大量脂质内含物和光合色素含量减少。
