Developmental Medicine Center, Boston Children's Hospital, and Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA.
Child Cognitive-Behavioral Therapy Program, Massachusetts General Hospital, and Harvard Medical School, 151 Merrimac Street, 3rd Floor, Boston, MA, 02114, USA.
J Autism Dev Disord. 2020 Nov;50(11):3905-3920. doi: 10.1007/s10803-020-04446-y.
To address the paucity of cognitive-behavioral therapy (CBT) protocols available to treat anxiety in preschoolers with ASD, we piloted a family-centered CBT protocol in a series of 16 children aged 3-7 years with ASD and anxiety disorders and explored its feasibility and efficacy. Children were assessed at baseline, post-treatment (PT), and 4-month follow-up (FU) using diagnostic interviews and parent questionnaires. Fourteen children completed at least 10 sessions (mean 14). At PT, 81% were rated "very much-" or "much-improved" on the CGI-Anxiety. Children displayed significant decreases on clinician- and parent-rated anxiety, and improved family function and coping. Gains were maintained at FU. Parent-child CBT is feasible for young children with ASD plus anxiety that shows potential for similar efficacy as with neurotypical children.
为了解决针对自闭症谱系障碍（ASD）学龄前儿童的焦虑症的认知行为疗法（CBT）方案不足的问题，我们对 16 名年龄在 3-7 岁的 ASD 伴焦虑障碍的儿童进行了一系列以家庭为中心的 CBT 方案试点，并探讨了其可行性和疗效。在基线、治疗后（PT）和 4 个月随访（FU）时，使用诊断访谈和家长问卷对儿童进行评估。14 名儿童完成了至少 10 个疗程（平均 14 个）。在 PT 时，81%的儿童在 CGI-Anxiety 上被评为“非常明显”或“明显改善”。儿童的焦虑症在临床医生和家长评定中显著降低，家庭功能和应对能力得到改善。在 FU 时，疗效保持。针对 ASD 合并焦虑症的幼儿进行的亲子认知行为疗法是可行的，其疗效可能与神经典型儿童相似。
