Department of Medicine, Cardiovascular Section, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Boulevard, AAT 5400, Oklahoma City, OK 73131, USA.
Department of Medicine, Cardiovascular Section, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Boulevard, AAT 5400, Oklahoma City, OK 73131, USA.
Interv Cardiol Clin. 2020 Apr;9(2):221-228. doi: 10.1016/j.iccl.2019.12.002. Epub 2020 Jan 31.
Acute limb ischemia (ALI) is a sudden decrease in limb perfusion that threatens limb viability. Using the Rutherford classification, limbs can be categorized as threatened but viable, or irreversibly damaged, which aids clinicians in selecting appropriate therapy. Treatment options for threatened limbs include catheter-directed thrombolysis, percutaneous mechanical thrombectomy, and surgical revascularization. Potential complications from ALI and treatment include ischemia-reperfusion injury, compartment syndrome, systemic inflammatory response syndrome, multiple organ dysfunction syndrome, hyperkalemia, and bleeding.
急性肢体缺血(ALI)是一种威胁肢体存活的肢体灌注突然减少。采用 Rutherford 分类法,肢体可分为有威胁但有活力的肢体,或不可逆转损伤的肢体,这有助于临床医生选择合适的治疗方法。有威胁的肢体的治疗选择包括导管定向溶栓、经皮机械血栓切除术和血管重建术。ALI 和治疗的潜在并发症包括缺血再灌注损伤、间隔综合征、全身炎症反应综合征、多器官功能障碍综合征、高钾血症和出血。