Hospital of the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Hospital of the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Interv Cardiol Clin. 2020 Apr;9(2):229-241. doi: 10.1016/j.iccl.2019.12.003. Epub 2020 Feb 10.
Treatment of acute pulmonary embolism (PE) historically included anticoagulation and systemic thrombolytic therapy. More recently, catheter guided interventions provided promise of mitigating bleeding risks usually associated with systemic thrombolysis in intermediate to high risk PE patients. Catheter based interventions can broadly be divided into catheter directed thrombolysis and catheter based embolectomy. Both modalities are currently undergoing active research and each has their respective risks and benefits. The decision to administer these advanced therapies for acute PE can be challenging but can be accomplished via a multi-disciplinary PE response team.
急性肺栓塞(PE)的治疗传统上包括抗凝和全身溶栓治疗。最近,导管引导的介入治疗为中高危 PE 患者提供了降低与全身溶栓相关出血风险的希望。导管介入治疗大致可分为导管直接溶栓和导管取栓。这两种方法都在进行积极的研究,各自有其风险和获益。对于急性 PE 给予这些先进治疗的决策可能具有挑战性,但可以通过多学科的 PE 反应团队来完成。