Fox G Q
Max-Planck-Institut für biophysikalische Chemie, Göttingen, F.R.G.
Brain Res. 1988 Dec 13;475(1):103-17. doi: 10.1016/0006-8993(88)90203-x.
Synaptic vesicle populations have been morphometrically analyzed for size and density. Populations composed of a single size class of vesicles are represented by normal (Gaussian) or positive (log-normal) skew histograms. Populations with multiple size classes generate negative (left) skew distributions. Fixatives containing aldehydes differentially affect these distribution patterns but vesicles are able to withstand tonic effects over a wide range. Reader bias' contribute the most error in the data-collecting process. But despite this, the sizing of vesicle populations can be accomplished with great accuracy. Vesicle density computations, on the other hand, vary over a wide range and are of less value for comparative purposes.
已对突触小泡群体进行了大小和密度的形态计量学分析。由单一大小类别的小泡组成的群体由正态（高斯）或正（对数正态）偏态直方图表示。具有多个大小类别的群体产生负（左）偏态分布。含有醛的固定剂对这些分布模式有不同的影响，但小泡能够在很宽的范围内承受张力作用。在数据收集过程中，“读者偏差”造成的误差最大。但尽管如此，小泡群体大小的测定仍可非常精确地完成。另一方面，小泡密度计算结果差异很大，用于比较目的时价值较小。
