Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Dept of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
Pancreatology. 2020 Apr;20(3):338-346. doi: 10.1016/j.pan.2020.02.005. Epub 2020 Feb 21.
BACKGROUND/OBJECTIVES: In Finland the incidence of chronic pancreatitis (CP) is high compared to that in most European countries. Recent epidemiological data is lacking. Our aim was to investigate the current epidemiologic and behavioural data on CP patients in Finland.
CP patients according to M-ANNHEIM criteria in Tampere University Hospital (TAUH) during 2014-2015 were included. Aetiology, time from diagnosis, pancreatic function, treatment, complications, smoking, alcohol consumption (AUDIT) and quality of life (QoL) (QLQ C30, PAN26) were gathered.
235 CP patients (57 (26-88) years, 65% men) were included. Time since diagnosis was 5.5 (1-41) years. Aetiology was alcohol in 67%, and smoking contributed in 54%. Of these patients 78% continued smoking and 58% continued to consume alcohol even after CP diagnosis. CP related complications were common. Pseudocysts were more common in alcohol related CP than in non-alcohol related CP (60% vs. 38%, p < 0.05). Reported QoL and pain were worse in the CP patients than in controls. Alcohol consumption differed from that of the Finnish population; the CP patients were either total abstainers or heavy alcohol consumers.
CP constitutes a great burden on the health care system and on the patients. The patients frequently develop complications and symptoms and their QoL is inferior to that of controls. The most important measure to halt the progression of CP would be to prevent acute phases and for patients to stop smoking, which does not happen in many CP patients. It would be beneficial to increase awareness among CP patients and medical professionals.
背景/目的：与大多数欧洲国家相比，芬兰的慢性胰腺炎（CP）发病率较高。最近缺乏流行病学数据。我们的目的是调查芬兰 CP 患者目前的流行病学和行为数据。
纳入 2014-2015 年在坦佩雷大学医院（TAUH）根据 M-ANNHEIM 标准诊断的 CP 患者。收集病因、从诊断到现在的时间、胰腺功能、治疗、并发症、吸烟、饮酒（AUDIT）和生活质量（QLQ C30、PAN26）。
共纳入 235 例 CP 患者（57（26-88）岁，65%为男性）。从诊断到现在的时间为 5.5（1-41）年。病因是酒精占 67%，吸烟占 54%。这些患者中有 78%继续吸烟，58%即使在 CP 诊断后仍继续饮酒。CP 相关并发症很常见。酒精性 CP 比非酒精性 CP 更常见假性囊肿（60%比 38%，p<0.05）。报告的生活质量和疼痛在 CP 患者中比在对照组中更差。饮酒不同于芬兰人群；CP 患者要么完全戒酒，要么是重度饮酒者。
CP 给医疗保健系统和患者带来了巨大负担。患者经常出现并发症和症状，生活质量低于对照组。阻止 CP 进展的最重要措施是预防急性发作，让患者戒烟，但许多 CP 患者都没有做到这一点。提高 CP 患者和医务人员的认识将是有益的。
