Department of Radiology, Istanbul Medeniyet University School of Medicine, Istanbul, Turkey.
Department of Otorhinolaryngology - Head and Neck Surgery, Istanbul Medeniyet University School of Medicine, İstanbul, Turkey.
J Int Adv Otol. 2021 Jan;17(1):1-8. doi: 10.5152/iao.2020.7863.
This study used the data from patients with congenital sensorineural hearing loss (CSNHL) and those with normal hearing to measure and compare the length of the cochlea with high-resolution computed tomography (HRCT).
HRCT images of patients who were diagnosed with CSNHL and were candidates for cochlear implantation were evaluated retrospectively. Sixty-three ears of 33 patients were included in the study. The control group comprised 66 ears of 33 individuals. The measurements were conducted by an experienced radiologist, using three-dimensional curved multiplanar reconstruction. All the measurements were performed thrice, and the average was calculated.
The data were distributed normally. The lengths of the cochlear components for the CSNHL and control groups were as follows: basal turn 21.66±1.01 (21.30-22.02) and 22.57±0.68 (22.32-22.81) mm, middle turn 11.58±0.69 (11.34-11.83) and 12.39±0.46 (12.23-12.56) mm, and apical turn 6.45±0.92 (6.12-6.77) and 7.12±0.65 (6.89-7.35) mm, respectively. The mean cochlear lateral wall (LW) length was significantly shorter in the CSNHL patients [39.71±1.32 (39.25-40.18) mm] than in the controls [42.09±1.17 (41.67-42.51) mm], (p<0.001). The intra-rater reliability was 0.878 (confidence interval 95%: 0.841-0.908 p<0.001). The cut-off value was 40.81 mm (sensitivity: 0.91, specificity: 0.94, and accuracy: 0.90).
There were microanatomic dissimilarities between the length of the cochlea in subjects from the CSNHL group and those from the control group.
本研究利用先天性感觉神经性听力损失（CSNHL）患者和听力正常患者的数据，通过高分辨率计算机断层扫描（HRCT）来测量和比较耳蜗长度。
回顾性评估了被诊断为 CSNHL 并需要进行人工耳蜗植入的患者的 HRCT 图像。共纳入 33 名患者的 63 只耳朵作为研究组，纳入 33 名个体的 66 只耳朵作为对照组。由一位经验丰富的放射科医生使用三维曲面多平面重建进行测量。所有测量均进行 3 次，取平均值。
数据呈正态分布。CSNHL 组和对照组的耳蜗各部位长度如下：底回 21.66±1.01（21.30-22.02）和 22.57±0.68（22.32-22.81）mm，中回 11.58±0.69（11.34-11.83）和 12.39±0.46（12.23-12.56）mm，顶回 6.45±0.92（6.12-6.77）和 7.12±0.65（6.89-7.35）mm。CSNHL 患者的耳蜗外侧壁（LW）长度平均值明显短于对照组[39.71±1.32（39.25-40.18）mm]，差异有统计学意义（p<0.001）。内部观察者信度为 0.878（置信区间 95%：0.841-0.908，p<0.001）。截断值为 40.81mm（敏感性：0.91，特异性：0.94，准确性：0.90）。
CSNHL 组和对照组患者的耳蜗长度存在微小的解剖学差异。
