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[藤仓赤霉菌中赤霉素的生物合成与代谢调控研究进展]

[Research progress in biosynthesis and metabolism regulation of gibberellins in Gibberella fujikuroi].

作者信息

Wang Bingxuan, Si Wen, Wu Yefei, Zhang Xinqi, Wang Shiying, Wu Choufei, Lin Haiping, Yin Lianghong

机构信息

Local and National Joint Engineering Laboratory of Biopesticide High-efficient Preparation, Zhejiang Agriculture and Forestry University, Lin'An 311300, Zhejiang, China.

Zhejiang Qianjiang Biochemical Co., Ltd., Haining 314400, Zhejiang, China.

出版信息

Sheng Wu Gong Cheng Xue Bao. 2020 Feb 25;36(2):189-200. doi: 10.13345/j.cjb.190194.

Abstract

Gibberellin is one of the most important plant growth regulators, and widely used in agricultural production. However, the high cost of gibberellins production is restricting its efficient application. In recent years, biotechnological innovations have improved the synthesis of gibberellin. Gibberellin biosynthesis requires various enzymes. Current research focuses on the biosynthetic mechanisms of gibberellin and the metabolic engineering techniques to improve the production of gibberellin. This paper reviews the current research on gibberellin biosynthesis pathway, the key and enzymes environmental factors involved, and the metabolic regulation of gibberellin in Gibberella fujikuroi, summarizes the application of metabolic regulation in gibberellin biosynthesis, to provide the basis for achieving stable gibberellins production.

摘要

赤霉素是最重要的植物生长调节剂之一,在农业生产中广泛应用。然而,赤霉素生产成本高昂,限制了其有效应用。近年来,生物技术创新改进了赤霉素的合成。赤霉素生物合成需要多种酶。目前的研究集中在赤霉素的生物合成机制以及提高赤霉素产量的代谢工程技术上。本文综述了目前关于赤霉菌中赤霉素生物合成途径、关键酶和环境因素以及赤霉素代谢调控的研究,总结了代谢调控在赤霉素生物合成中的应用,为实现赤霉素的稳定生产提供依据。

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