Department of Obstetrics & Gynecology, The People's Hospital of Yingshang, Anhui 236200, PR China.
Department of Neurology, Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, PR China.
Future Oncol. 2020 Apr;16(10):525-540. doi: 10.2217/fon-2020-0017. Epub 2020 Mar 9.
Our aim was to analyze the clinicopathological features of lung, liver, bone and brain metastasis in patients with endometrial cancer (EC). We screened patients diagnosed with EC between 2010 and 2015 from the Surveillance, Epidemiology and End Results database. Among 69,027 eligible EC patients, lung metastasis was the most common. Patients with lung or liver metastasis were at higher risk of bone and brain metastases than those without lung and liver metastasis. Brain metastasis has the lowest survival time (5.0 months) in single organ metastasis. Liver and brain metastasis have the highest death rate in two organ metastasis, and lung, liver and brain metastasis had the lowest survival time (1.0 month) in multi-sites metastasis. Lung metastasis was the most common in EC patients. Assessing distant organ metastasis may help clinicians to determine appropriate follow-up strategy for patients with EC.
我们旨在分析子宫内膜癌（EC）患者肺、肝、骨和脑转移的临床病理特征。我们从监测、流行病学和最终结果数据库中筛选了 2010 年至 2015 年间诊断为 EC 的患者。在 69027 名符合条件的 EC 患者中，肺转移最为常见。与无肺和肝转移的患者相比，有肺或肝转移的患者发生骨和脑转移的风险更高。脑转移在单一器官转移中具有最低的生存时间（5.0 个月）。肝和脑转移在两个器官转移中具有最高的死亡率，肺、肝和脑转移在多部位转移中具有最低的生存时间（1.0 个月）。肺转移是 EC 患者中最常见的。评估远处器官转移可能有助于临床医生为 EC 患者确定合适的随访策略。
