• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

默克尔细胞癌及一家参考医院的诊断经验:病例系列

Merkel Cell Carcinoma and Diagnostic Experience in a Reference Hospital: A Case Series.

作者信息

López Panqueva Rocio Del Pilar, Suarez-Zamora David A, Barrera-Herrera Luis E, Rolón Cadena Mariam

机构信息

Department of Pathology and Laboratories, Fundación Santa Fe de Bogotá, Bogotá, Colombia.

Faculty of Medicine, Universidad de Los Andes, Bogotá, Colombia.

出版信息

Case Rep Med. 2020 Feb 19;2020:8391510. doi: 10.1155/2020/8391510. eCollection 2020.

DOI:10.1155/2020/8391510
PMID:32148513
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7049825/
Abstract

Merkel cell carcinoma (MCC) is a rare poorly differentiated neuroendocrine tumor, usually located in sun-exposed skin, with aggressive behavior and with high recurrence risk and metastatic disease. In Latin America, case series have been published, and it does not exceed 32 patients in 10 years, and in Colombia, there are case reports. We present a descriptive retrospective cross-sectional study in patients diagnosed with MCC in the Department of Pathology and Laboratories at the University Hospital Fundación Santa Fe de Bogotá(FSFB) between January 2003 and December 2018. We present the demographic, clinical, and pathological variables of these patients, as well as a literature review.

摘要

默克尔细胞癌(MCC)是一种罕见的低分化神经内分泌肿瘤,通常位于暴露于阳光下的皮肤,具有侵袭性,复发风险高且易发生转移性疾病。在拉丁美洲,已有病例系列发表,10年内患者不超过32例,在哥伦比亚也有病例报告。我们对2003年1月至2018年12月期间在波哥大圣菲德波哥大基金会大学医院(FSFB)病理科和实验室诊断为MCC的患者进行了一项描述性回顾性横断面研究。我们展示了这些患者的人口统计学、临床和病理变量,并进行了文献综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb10/7049825/763e22e8a7a0/CRIM2020-8391510.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb10/7049825/cbe37cb6bc9d/CRIM2020-8391510.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb10/7049825/763e22e8a7a0/CRIM2020-8391510.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb10/7049825/cbe37cb6bc9d/CRIM2020-8391510.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb10/7049825/763e22e8a7a0/CRIM2020-8391510.002.jpg

相似文献

1
Merkel Cell Carcinoma and Diagnostic Experience in a Reference Hospital: A Case Series.默克尔细胞癌及一家参考医院的诊断经验:病例系列
Case Rep Med. 2020 Feb 19;2020:8391510. doi: 10.1155/2020/8391510. eCollection 2020.
2
Merkel Cell Carcinoma of the Buccal Mucosa and Lower Lip.颊黏膜和下唇的默克尔细胞癌
Head Neck Pathol. 2018 Jun;12(2):279-285. doi: 10.1007/s12105-017-0859-1. Epub 2017 Oct 4.
3
Recent Therapeutic Advances and Change in Treatment Paradigm of Patients with Merkel Cell Carcinoma.最近默克尔细胞癌患者的治疗进展和治疗模式的改变。
Oncologist. 2019 Oct;24(10):1375-1383. doi: 10.1634/theoncologist.2018-0718. Epub 2019 Apr 8.
4
Increasing tumor thickness is associated with recurrence and poorer survival in patients with Merkel cell carcinoma.肿瘤厚度的增加与 Merkel 细胞癌患者的复发和生存状况较差相关。
Ann Surg Oncol. 2012 Oct;19(11):3325-34. doi: 10.1245/s10434-012-2509-x. Epub 2012 Jul 21.
5
Merkel cell carcinoma: our experience in this rare pathology. Merkel 细胞癌:我们在这种罕见病理学中的经验。
Med Oral Patol Oral Cir Bucal. 2011 Sep 1;16(6):e736-9. doi: 10.4317/medoral.17068.
6
Merkel cell carcinoma with divergent differentiation.具有分化趋异的 Merkel 细胞癌。
Clin Exp Dermatol. 2020 Apr;45(3):327-332. doi: 10.1111/ced.14110. Epub 2019 Nov 13.
7
Merkel cell carcinoma of the skin and mucosa: report of 12 cutaneous cases with 2 cases arising from the nasal mucosa.皮肤和黏膜的默克尔细胞癌:12例皮肤病例报告,其中2例起源于鼻黏膜。
Dermatol Surg. 2001 Feb;27(2):165-70. doi: 10.1046/j.1524-4725.2001.00189.x.
8
Unexpected maspin immunoreactivity in Merkel cell carcinoma.默克尔细胞癌中意外出现的乳腺丝抑蛋白免疫反应性。
Diagn Pathol. 2015 Nov 25;10:206. doi: 10.1186/s13000-015-0437-3.
9
Merkel cell carcinoma: An update and review: Current and future therapy. Merkel 细胞癌:更新与综述:当前与未来的治疗。
J Am Acad Dermatol. 2018 Mar;78(3):445-454. doi: 10.1016/j.jaad.2017.12.004. Epub 2017 Dec 9.
10
Merkel cell carcinoma: An update and review: Pathogenesis, diagnosis, and staging. Merkel 细胞癌:最新研究和综述:发病机制、诊断和分期。
J Am Acad Dermatol. 2018 Mar;78(3):433-442. doi: 10.1016/j.jaad.2017.12.001. Epub 2017 Dec 9.

引用本文的文献

1
Merkel Cell Carcinoma: From Pathobiology to Clinical Management.默克尔细胞癌:从病理生物学到临床管理
Biology (Basel). 2021 Dec 8;10(12):1293. doi: 10.3390/biology10121293.

本文引用的文献

1
Association of Phenotypic Characteristics and UV Radiation Exposure With Risk of Melanoma on Different Body Sites.表型特征和紫外线辐射暴露与不同身体部位黑素瘤风险的关联。
JAMA Dermatol. 2019 Jan 1;155(1):39-49. doi: 10.1001/jamadermatol.2018.3964.
2
The biology and treatment of Merkel cell carcinoma: current understanding and research priorities.默克尔细胞癌的生物学和治疗:当前的认识和研究重点。
Nat Rev Clin Oncol. 2018 Dec;15(12):763-776. doi: 10.1038/s41571-018-0103-2.
3
Merkel cell carcinoma: An update and review: Pathogenesis, diagnosis, and staging.
Merkel 细胞癌:最新研究和综述:发病机制、诊断和分期。
J Am Acad Dermatol. 2018 Mar;78(3):433-442. doi: 10.1016/j.jaad.2017.12.001. Epub 2017 Dec 9.
4
Merkel cell carcinoma: Epidemiology, pathogenesis, diagnosis and therapy.默克尔细胞癌:流行病学、发病机制、诊断与治疗。
Rev Endocr Metab Disord. 2017 Dec;18(4):517-532. doi: 10.1007/s11154-017-9433-0.
5
Age and Gender Associations of Virus Positivity in Merkel Cell Carcinoma Characterized Using a Novel RNA Hybridization Assay.采用新型 RNA 杂交检测方法分析 Merkel 细胞癌中病毒阳性与年龄和性别的关系。
Clin Cancer Res. 2017 Sep 15;23(18):5622-5630. doi: 10.1158/1078-0432.CCR-17-0299. Epub 2017 Jun 12.
6
Merkel cell carcinoma: Epidemiology, prognosis, therapy and unmet medical needs.默克尔细胞癌:流行病学、预后、治疗和未满足的医疗需求。
Eur J Cancer. 2017 Jan;71:53-69. doi: 10.1016/j.ejca.2016.10.022. Epub 2016 Dec 14.
7
UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas.UV 相关突变是 MCV 阴性 Merkel 细胞癌发病机制的基础。
Cancer Res. 2015 Dec 15;75(24):5228-34. doi: 10.1158/0008-5472.CAN-15-1877. Epub 2015 Dec 1.
8
Dramatic Increase in the Incidence and Mortality from Merkel Cell Carcinoma in the United States.美国默克尔细胞癌的发病率和死亡率急剧上升。
Am Surg. 2015 Aug;81(8):802-6. doi: 10.1177/000313481508100819.
9
A case series and literature review of Merkel cell carcinoma metastasizing to pancreas.Merkel细胞癌转移至胰腺的病例系列及文献综述
Dig Dis Sci. 2015 Jun;60(6):1805-12. doi: 10.1007/s10620-014-3516-5. Epub 2015 Jan 14.
10
Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.195例默克尔细胞癌确诊时的临床特征:AEIOU特征
J Am Acad Dermatol. 2008 Mar;58(3):375-81. doi: 10.1016/j.jaad.2007.11.020.