Haghighat Sara, Rezazadeh Fahimeh
Department of Oral and Maxillofacial Medicine, Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Oral and Maxillofacial Medicine, Oral and Dental Diseases Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran J Microbiol. 2019 Oct;11(5):357-362.
Oral mucosal infections are an important type of oral lesions. The aim of this study was to determine the epidemiology of oral mucosal infectious lesions in patients who referred to Oral Medicine Department of Shiraz Dental School, Iran during 11 years.
In this cross sectional study, records of all patients who referred to Oral Medicine Department of Shiraz Dental School from September 2007 to January 2018 were assessed and those data sheets which their definitive diagnosis were a kind of oral mucosal infectious lesion were recorded. Pearson Chi-square test was used for statistical analysis. Level of significance was considered as P value < 0.05.
Overall prevalence of oral mucosal infectious lesions was 9.47%. Generally, mean age of patients was 42.92 ± 18.84 and most of them were female. Most common type of infectious lesions was fungal infections, but viral and bacterial infections were less common. Among fungal infections, most lesions were candidiasis and only 3 cases were diagnosed as deep fungal infection. HSV infection was the second common oral infectious lesion. There was a significant relation between infectious lesion and systemic disease or medication use (P=0.000).
This study is the first epidemiologic study in Iran, concerning oral mucosal infectious lesions. Total of 9.47% of oral lesions were infective, candidiasis and HSV lesions were the most common oral mucosal infective disease, which were more prevalent amongst female, middle age people and patients with systemic disease.
口腔黏膜感染是口腔病变的重要类型。本研究旨在确定在11年期间转诊至伊朗设拉子牙科学院口腔内科的患者中口腔黏膜感染性病变的流行病学情况。
在这项横断面研究中,对2007年9月至2018年1月期间转诊至设拉子牙科学院口腔内科的所有患者的记录进行了评估,并记录了最终诊断为某种口腔黏膜感染性病变的数据表。采用Pearson卡方检验进行统计分析。显著性水平被认为是P值<0.05。
口腔黏膜感染性病变的总体患病率为9.47%。一般来说,患者的平均年龄为42.92±18.84岁,其中大多数为女性。最常见的感染性病变类型是真菌感染,但病毒和细菌感染较少见。在真菌感染中,大多数病变为念珠菌病,只有3例被诊断为深部真菌感染。单纯疱疹病毒(HSV)感染是第二常见的口腔感染性病变。感染性病变与全身疾病或药物使用之间存在显著关联(P=0.000)。
本研究是伊朗关于口腔黏膜感染性病变的首次流行病学研究。9.47%的口腔病变为感染性病变,念珠菌病和HSV病变是最常见的口腔黏膜感染性疾病,在女性、中年人和患有全身疾病的患者中更为普遍。