Wang Jia-Lin, Wang Yan-Ling
Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yongan Road, Xicheng District, Beijing, China.
J Ophthalmol. 2020 Feb 21;2020:2074037. doi: 10.1155/2020/2074037. eCollection 2020.
To investigate the outcome of pars plana vitrectomy (PPV) with suitable internal limiting membrane peeling (ILM) and air tamponade for patients with highly myopic foveoschisis-associated lamellar macular hole (MH).
This retrospective interventional case series included 11 patients with highly myopic foveoschisis-associated lamellar MH who underwent PPV and indocyanine green-aided ILM peeling up to the temporal vascular arcades. Following air tamponade after surgery, all patients were instructed to maintain a face-down position. The patients were followed up for over 1 year and evaluated for MH closure and the best-corrected visual acuity before and after surgery.
The mean ± standard deviation values of patient age, axial length, and follow-up duration were 67.82 ± 6.54 years, 29.21 ± 1.95 mm, and 24.27 ± 8.11 months, respectively. After surgery, the lamellar MH closed in all eyes, and 10 eyes showed vision improvement at the 1-month, 3-month, and final follow-up evaluations. One patient showed decreased vision at 2 years after surgery, with patchy chorioretinal atrophy in the macular region. Myopic foveoschisis showed resolution in three eyes and alleviation in eight. Ten patients underwent cataract surgery during PPV.
Extension of ILM peeling up to the temporal vascular arcades and air tamponade after PPV may improve the visual function and rate of MH closure for patients with highly myopic foveoschisis-associated lamellar MH.
探讨对于高度近视性黄斑劈裂相关板层黄斑裂孔(MH)患者,采用合适的内界膜剥除(ILM)联合空气填充的玻璃体切除术(PPV)的治疗效果。
本回顾性干预性病例系列研究纳入了11例高度近视性黄斑劈裂相关板层MH患者,这些患者接受了PPV及吲哚菁绿辅助下的ILM剥除,剥除范围达颞侧血管弓。术后空气填充后,所有患者均被要求保持面朝下体位。对患者进行了超过1年的随访,并评估了MH闭合情况以及手术前后的最佳矫正视力。
患者年龄、眼轴长度及随访时间的平均值±标准差分别为67.82±6.54岁、29.21±1.95mm和24.27±8.11个月。术后,所有患眼的板层MH均闭合,10只眼在1个月、3个月及最终随访评估时视力得到改善。1例患者在术后2年视力下降,黄斑区有散在的脉络膜视网膜萎缩。3只眼的近视性黄斑劈裂得到缓解,8只眼有所减轻。10例患者在PPV期间接受了白内障手术。
PPV后将ILM剥除范围扩展至颞侧血管弓并进行空气填充,可能会改善高度近视性黄斑劈裂相关板层MH患者的视功能及MH闭合率。