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一名女性患者出现多例异时性和同时性原发性癌症的罕见情况。

An Unusual Occurrence of Multiple Metachronous and Synchronous Primary Cancers in a Female Patient.

作者信息

Torina Tyler B, Hudspeth Emily L, Chun Joon Min, Zaloga William, Alderink Carlisle, Abdeen Yazan

机构信息

Mercy Hospital Fort Smith, Arkansas College of Osteopathic Medicine, USA.

出版信息

Case Rep Oncol Med. 2020 Feb 18;2020:5691732. doi: 10.1155/2020/5691732. eCollection 2020.

Abstract

Multiple primary cancers, although uncommon, have been increasing in incidence in recent years. This trend is likely due to advances in factors such as diagnostic imaging, life expectancy, and interventional modalities with associated adverse effects. The patient presented in this case report is a 59-year-old Caucasian female with an extensive medical history who developed multiple primary cancers of the breast, mouth, gastrointestinal system, and lung in the span of four years. We attempted to elucidate the possible etiologies and risk factors that may have contributed. Given the patient's complex medical and social history, interventions, environmental, and genetic predispositions, it is impossible to pinpoint a single etiology. Rather, it is more likely that the interplay of multiple factors contributed to the findings of this case.

摘要

多原发性癌症虽然不常见,但近年来发病率一直在上升。这种趋势可能归因于诊断成像、预期寿命和具有相关副作用的介入治疗方式等因素的进步。本病例报告中的患者是一名59岁的白种女性,有广泛的病史,在四年内患上了乳腺癌、口腔癌、胃肠道癌和肺癌等多原发性癌症。我们试图阐明可能起作用的病因和危险因素。鉴于患者复杂的医疗和社会病史、干预措施、环境因素和遗传易感性,不可能确定单一病因。相反,更有可能是多种因素的相互作用导致了本病例的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd59/7049841/5bbdbd5d7191/CRIONM2020-5691732.001.jpg

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