Department of Occupational Medicine, Chi-Mei Medical Center, Tainan, 710, Taiwan.
Department of Surveillance, Centers for Disease Control, Taipei, 100, Taiwan.
Int J Environ Res Public Health. 2020 Mar 5;17(5):1686. doi: 10.3390/ijerph17051686.
Mumps is an important childhood infectious disease caused by mumps virus (MuV). We reviewed the epidemiology, pathogenesis, and vaccine development of mumps. Previous studies were identified using the key words "mumps" and "epidemiology", "pathogenesis" or "vaccine" in MEDLINE, PubMed, Embase, Web of Science, and Google Scholar. We excluded the articles that were not published in the English language, manuscripts without abstracts, and opinion articles from the review. The number of cases caused by MuV decreased steeply after the introduction of the mumps vaccine worldwide. In recent years, a global resurgence of mumps cases in developed countries and cases of aseptic meningitis caused by some mumps vaccine strains have renewed the importance of MuV infection worldwide. The performance of mumps vaccination has become an important issue for controlling mumps infections. Vaccine development and routine vaccination are still effective measures to globally reduce the incidence of mumps infections. During outbreaks, a third of MMR vaccine is recommended for groups of persons determined by public authorities.
流行性腮腺炎是由腮腺炎病毒（MuV）引起的一种重要的儿童传染病。我们综述了流行性腮腺炎的流行病学、发病机制和疫苗开发。使用 MEDLINE、PubMed、Embase、Web of Science 和 Google Scholar 中的关键词“流行性腮腺炎”和“流行病学”、“发病机制”或“疫苗”来确定先前的研究。我们排除了非英文发表的文章、无摘要的手稿和观点文章。全球引入腮腺炎疫苗后，由 MuV 引起的病例数量急剧下降。近年来，发达国家流行性腮腺炎病例的全球再现以及某些腮腺炎疫苗株引起的无菌性脑膜炎病例，使 MuV 感染在全球范围内再次受到重视。腮腺炎疫苗接种的效果成为控制腮腺炎感染的重要问题。疫苗开发和常规疫苗接种仍然是全球减少腮腺炎感染发病率的有效措施。在暴发期间，建议由公共当局确定的人群接种三分之一的麻疹、腮腺炎和风疹联合疫苗。
