Ludolph A C, Husstedt I W, Schlake H P, Grotemeyer K H, Brune G G
Department of Neurology, University of Münster, FRG.
Eur Neurol. 1988;28(6):311-6. doi: 10.1159/000116292.
22 migraine patients with a history of chronic ergotamine abuse were compared with 12 patients with a similar intake of dihydroergotamine. The study of somatosensory-evoked potentials showed that 50% of the patients with a history of ergotamine abuse had increased central conduction times after stimulation of the tibial nerve. Corticomotoneuronal latencies obtained by noninvasive electrical stimulation of the motor cortex were normal in 5 patients. The functional sensory deficits were not related to clinical impairment and were more frequently observed in patients with a comparatively high mean daily and cumulative intake.
将22名有慢性麦角胺滥用史的偏头痛患者与12名二氢麦角胺摄入量相似的患者进行了比较。体感诱发电位研究表明，有麦角胺滥用史的患者中，50%在刺激胫神经后中枢传导时间延长。通过对运动皮层进行无创电刺激获得的皮质运动神经元潜伏期，在5名患者中是正常的。功能性感觉缺陷与临床损伤无关，且在平均每日摄入量和累积摄入量相对较高的患者中更常观察到。
