• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

骶神经调控编程算法:临床实践和日常实践的证据推荐。

Programming Algorithms for Sacral Neuromodulation: Clinical Practice and Evidence-Recommendations for Day-to-Day Practice.

机构信息

Coloproctology Unit, Ospedale Regionale di Lugano, Lugano, Switzerland.

Department of Surgical and Medical Gastroenterology, Hvidovre University Hospital, Hvidovre, Denmark.

出版信息

Neuromodulation. 2020 Dec;23(8):1121-1129. doi: 10.1111/ner.13117. Epub 2020 Mar 9.

DOI:10.1111/ner.13117
PMID:32153080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7818413/
Abstract

BACKGROUND

In sacral neuromodulation (SNM), stimulation programming plays a key role to achieve success of the therapy. However to date, little attention has been given to the best ways to set and optimize SNM programming during the test and chronic stimulation phases of the procedure.

OBJECTIVE

Standardize and make SNM programming easier and more efficient for the several conditions for which SNM is proposed.

METHODS

Systematic literature review and collective clinical experience report.

RESULTS

The basic principles of SNM programming are described. It covers choice of electrode configuration, stimulation amplitude, pulse frequency and pulse widths, while use of cycling is also briefly discussed. Step-by-step practical flow charts developed by a group of 13 European experts are presented.

CONCLUSIONS

Programming of SNM therapy is not complex. There are few programming settings that seem beneficial or significantly impact patient outcomes. Only four basic electrode configurations could be identified according to four different options to define the cathode. In a majority of patients, the proposed stimulation parameters will allow a satisfactory improvement for long periods of time. A regular follow-up is, however, necessary to assess and eventually optimize results, as well as to reassure patients.

摘要

背景

在骶神经调节(SNM)中,刺激编程在实现治疗成功方面起着关键作用。然而,迄今为止,人们很少关注在该程序的测试和慢性刺激阶段设置和优化 SNM 编程的最佳方法。

目的

为 SNM 提出的几种情况标准化并简化 SNM 编程,使其更高效。

方法

系统文献回顾和集体临床经验报告。

结果

描述了 SNM 编程的基本原则。它涵盖了电极配置、刺激幅度、脉冲频率和脉冲宽度的选择,同时还简要讨论了循环的使用。由 13 位欧洲专家组成的小组制定了逐步实用的流程图。

结论

SNM 治疗的编程并不复杂。只有少数编程设置似乎有益或对患者的治疗效果有显著影响。根据定义阴极的四个不同选项,仅能确定四种基本的电极配置。对于大多数患者,所提出的刺激参数将在很长一段时间内允许令人满意的改善。然而,需要定期进行随访以评估和最终优化结果,并让患者安心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/04ff2e09fb4c/NER-23-1121-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/32af827b52d7/NER-23-1121-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/289e3d391b77/NER-23-1121-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/fdbf28800fcd/NER-23-1121-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/04ff2e09fb4c/NER-23-1121-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/32af827b52d7/NER-23-1121-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/289e3d391b77/NER-23-1121-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/fdbf28800fcd/NER-23-1121-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4820/7818413/04ff2e09fb4c/NER-23-1121-g004.jpg

相似文献

1
Programming Algorithms for Sacral Neuromodulation: Clinical Practice and Evidence-Recommendations for Day-to-Day Practice.骶神经调控编程算法:临床实践和日常实践的证据推荐。
Neuromodulation. 2020 Dec;23(8):1121-1129. doi: 10.1111/ner.13117. Epub 2020 Mar 9.
2
The science behind programming algorithms for sacral neuromodulation.骶神经调节编程算法背后的科学。
Colorectal Dis. 2021 Mar;23(3):592-602. doi: 10.1111/codi.15390. Epub 2020 Oct 25.
3
[Sacral Neuromodulation for Fecal Incontinence and Constipation: Evidence, Programming and Long-term Management].[骶神经调节治疗大便失禁和便秘:证据、程控与长期管理]
Zentralbl Chir. 2023 Jun;148(3):228-236. doi: 10.1055/a-2063-3630. Epub 2023 Jun 2.
4
Reprogramming Sacral Neuromodulation for Sub-Optimal Outcomes: Evidence and Recommendations for Clinical Practice.重新编程骶神经调节以改善次优结果:临床实践的证据和建议。
Neuromodulation. 2021 Oct;24(7):1247-1257. doi: 10.1111/ner.13494. Epub 2021 Jul 15.
5
Preliminary analysis of stimulation parameters for sacral neuromodulation in different indications: a multicenter retrospective cohort study from China.不同适应证下骶神经调控刺激参数的初步分析:来自中国的多中心回顾性队列研究。
Int J Surg. 2024 Jun 1;110(6):3536-3542. doi: 10.1097/JS9.0000000000001302.
6
Sacral Neuromodulation for Lower Urinary Tract and Bowel Dysfunction in Animal Models: A Systematic Review With Focus on Stimulation Parameter Selection.骶神经调控治疗动物模型下尿路和肠道功能障碍:基于刺激参数选择的系统评价
Neuromodulation. 2020 Dec;23(8):1094-1107. doi: 10.1111/ner.13245. Epub 2020 Aug 18.
7
Is Our Limited Understanding of the Effects of Nerve Stimulation Resulting in Poor Outcomes and the Need for Better "Rescue Programming" in SNM and PTNS, and Lost Opportunities for New Sites of Stimulation? ICI-RS 2024.我们对神经刺激效果的有限理解是否导致了不良结果,以及在骶神经调节和经皮胫神经刺激中需要更好的“挽救编程”,还有新刺激部位的机会流失?ICI-RS 2024。
Neurourol Urodyn. 2025 Mar;44(3):676-682. doi: 10.1002/nau.25600. Epub 2024 Oct 10.
8
Sensing in Sacral Neuromodulation: A Feasibility Study in Subjects With Urinary Incontinence and Retention.骶神经调节中的感应:一项在伴有尿失禁和潴留的患者中的可行性研究。
Neuromodulation. 2024 Feb;27(2):392-398. doi: 10.1016/j.neurom.2023.07.002. Epub 2023 Aug 16.
9
Sacral neuromodulation for lower urinary tract dysfunction.骶神经调节治疗下尿路功能障碍。
World J Urol. 2012 Aug;30(4):445-50. doi: 10.1007/s00345-011-0780-2. Epub 2011 Oct 12.
10
Sacral Neuromodulation: Standardized Electrode Placement Technique.骶神经调节:标准化电极放置技术。
Neuromodulation. 2017 Dec;20(8):816-824. doi: 10.1111/ner.12695. Epub 2017 Oct 4.

引用本文的文献

1
Factors Affecting Anal Sphincter Recruitment During Intraoperative Pudendal Nerve Stimulation: An Observational Study.术中阴部神经刺激期间影响肛门括约肌募集的因素:一项观察性研究。
Int Urogynecol J. 2025 Aug 13. doi: 10.1007/s00192-025-06238-3.
2
Sacral neuromodulation in patients with neurogenic lower urinary tract dysfunction.神经源性下尿路功能障碍患者的骶神经调节
Curr Urol. 2025 Jul;19(4):280-285. doi: 10.1097/CU9.0000000000000201. Epub 2023 May 23.
3
Acute Cortical Brain Neuroexcitation Can Be Detected With Sacral Neuromodulation.

本文引用的文献

1
Improved longevity and efficacy of sacral nerve stimulation by simple adjustments at follow-up.通过随访时的简单调整,提高了骶神经刺激的疗效和寿命。
Colorectal Dis. 2020 Mar;22(3):310-318. doi: 10.1111/codi.14874. Epub 2019 Oct 28.
2
Mapping the current flow in sacral nerve stimulation using computational modelling.利用计算模型绘制骶神经刺激中的电流流动情况。
Healthc Technol Lett. 2019 Jan 7;6(1):8-12. doi: 10.1049/htl.2018.5030. eCollection 2019 Feb.
3
Success and Complication Rates After Sacral Neuromodulation for Fecal Incontinence and Constipation: A Single-center Follow-up Study.
急性皮质脑神经兴奋可通过骶神经调节检测出来。
Urogynecology (Phila). 2025 Apr 1;31(4):344-351. doi: 10.1097/SPV.0000000000001657.
4
Differential effects of low- and high-frequency sacral neuromodulation on urinary symptoms: high-frequency improves Qmax, low-frequency enhances bladder capacity.低频和高频骶神经调节对泌尿症状的不同影响:高频改善最大尿流率,低频增加膀胱容量。
Am J Transl Res. 2025 Feb 15;17(2):1114-1124. doi: 10.62347/IGEX6196. eCollection 2025.
5
Management of Fecal Incontinence: Surgical Treatment Options.大便失禁的管理:手术治疗选择
Visc Med. 2024 Dec;40(6):318-324. doi: 10.1159/000541355. Epub 2024 Oct 7.
6
Sacral Neuromodulation: Device Improvement and Current Applications in Urology.骶神经调节:设备改进及在泌尿科的当前应用。
Medicina (Kaunas). 2024 Mar 20;60(3):509. doi: 10.3390/medicina60030509.
7
Pathways and parameters of sacral neuromodulation in rats.大鼠骶神经调节的途径和参数。
Am J Physiol Renal Physiol. 2023 Dec 1;325(6):F757-F769. doi: 10.1152/ajprenal.00123.2023. Epub 2023 Oct 5.
8
Electroceuticals for Neurogastroenterology and Motility Disorders.电刺激治疗在神经胃肠病学和运动障碍中的应用
Curr Gastroenterol Rep. 2023 Apr;25(4):91-97. doi: 10.1007/s11894-023-00866-9. Epub 2023 Mar 3.
9
Data Gap in Sacral Neuromodulation Documentation: Call to Improve Documentation Protocols.骶神经调节记录中的数据缺口:呼吁改进记录协议
Int Neurourol J. 2022 Sep;26(3):227-233. doi: 10.5213/inj.2244084.042. Epub 2022 Sep 30.
10
Faecal incontinence is associated with an impaired rectosigmoid brake and improved by sacral neuromodulation.大便失禁与直肠乙状结肠制动功能受损有关,并可通过骶神经调节得到改善。
Colorectal Dis. 2022 Dec;24(12):1556-1566. doi: 10.1111/codi.16249. Epub 2022 Jul 19.
骶神经调节治疗大便失禁和便秘后的成功率及并发症发生率:一项单中心随访研究
J Neurogastroenterol Motil. 2019 Jan 31;25(1):159-170. doi: 10.5056/jnm17106.
4
Repeatability of tools to assist in the follow up and troubleshooting of sacral neuromodulation patients using the sensory response.工具的可重复性,用于辅助骶神经调节患者使用感觉反应进行随访和故障排除。
Neurourol Urodyn. 2019 Feb;38(2):801-808. doi: 10.1002/nau.23925. Epub 2019 Jan 15.
5
Sacral neuromodulation using the standardized tined lead implantation technique with a curved vs a straight stylet: 2-year clinical outcomes and sensory responses to lead stimulation.采用标准化的带刺导丝植入技术进行骶神经调节:使用弯曲与直导丝的 2 年临床结果和对导丝刺激的感觉反应。
BJU Int. 2019 May;123(5A):E7-E13. doi: 10.1111/bju.14650. Epub 2019 Jan 13.
6
Troubleshooting Interstim Sacral Neuromodulation Generators to Recover Function.InterStim骶神经调节发生器故障排除以恢复功能。
Curr Urol Rep. 2018 Aug 20;19(10):86. doi: 10.1007/s11934-018-0837-5.
7
The functional outcome of sacral nerve stimulation for faecal incontinence can be improved by using lead model 3889 and a standardized implantation technique.采用 3889 型电极和标准化植入技术,可改善骶神经刺激治疗粪便失禁的功能效果。
Colorectal Dis. 2018 Jun;20(6):O152-O157. doi: 10.1111/codi.14234. Epub 2018 May 16.
8
International Continence Society best practice statement for use of sacral neuromodulation.国际尿控协会关于骶神经调节使用的最佳实践声明。
Neurourol Urodyn. 2018 Jun;37(5):1823-1848. doi: 10.1002/nau.23515. Epub 2018 Apr 11.
9
Electromyographic Responses Across Different Pulse-Widths of Sacral Neuromodulation in Sheep.羊体不同脉冲宽度骶神经调节的肌电图反应。
Neuromodulation. 2019 Aug;22(6):684-689. doi: 10.1111/ner.12779. Epub 2018 Apr 6.
10
Programming settings and recharge interval in a prospective study of a rechargeable sacral neuromodulation system for the treatment of overactive bladder.前瞻性研究可充电骶神经调节系统治疗膀胱过度活动症的编程设置和充电间隔。
Neurourol Urodyn. 2018 Feb;37(S2):S17-S22. doi: 10.1002/nau.23476. Epub 2018 Jan 16.