自噬抑制乳腺癌转移。
Autophagy Suppresses Breast Cancer Metastasis.
机构信息
Laboratory of Systems Cancer Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
出版信息
Dev Cell. 2020 Mar 9;52(5):542-544. doi: 10.1016/j.devcel.2020.02.005.
PMID:32155434
Abstract
Cancer cells need to acquire specific molecular traits in order to spread to distant organs. In this issue of Developmental Cell, Marsh et al. show that autophagy restricts the outgrowth of breast cancer metastases in contrast to its impact on primary tumor progression.
摘要
癌细胞需要获得特定的分子特征才能扩散到远处的器官。在本期《发育细胞》中，Marsh 等人表明，自噬限制了乳腺癌转移的生长，而不是像其对原发性肿瘤进展的影响那样。
Zotero 插件