Varela-Castro Lucía, Torrontegi Olalla, Sevilla Iker A, Barral Marta
NEIKER-Instituto Vasco de Investigación y Desarrollo Agrario, Animal Health Department, Bizkaia Science and Technology Park 812L, 48160 Derio (Bizkaia), Spain.
Microorganisms. 2020 Mar 6;8(3):374. doi: 10.3390/microorganisms8030374.
Mycobacterial infections caused by the complex (MTC) and non-tuberculous mycobacteria (NTM) are of great medical and veterinary relevance. The aim of this research was to study whether small mammals play a role in the epidemiology of mycobacterioses. Four samplings of 100 traps were performed in each of three cattle farms with previous history of tuberculosis or NTM between 2017 and 2018. A total of 108 animals belonging to seven species were trapped, classified, and necropsied, and tissues were submitted to microbiological and molecular methods for mycobacteria identification. The wood mouse () was the most abundant species (87%). No MTC was detected but six different NTM were identified (, subsp. , , , and a not determined sp.), showing a prevalence of 6.5%. No significant association was found between mycobacteria prevalence and the analyzed factors. Although a role in the epidemiology of MTC could not be attributed to small mammals, . carries NTM that could be pathogenic or interfere with the diagnosis of tuberculosis. According to our results, there is a risk of NTM transmission at the wildlife-livestock interface through potential indirect contacts between small mammals and cattle.
由结核分枝杆菌复合群（MTC）和非结核分枝杆菌（NTM）引起的分枝杆菌感染在医学和兽医学上具有重要意义。本研究的目的是研究小型哺乳动物在分枝杆菌病流行病学中是否起作用。2017年至2018年期间，在三个有结核病或NTM病史的奶牛场中，每个奶牛场用100个捕鼠器进行了四次采样。共捕获、分类并解剖了属于七个物种的108只动物，并将组织提交给微生物学和分子方法进行分枝杆菌鉴定。林姬鼠（）是数量最多的物种（87%）。未检测到MTC，但鉴定出六种不同的NTM（、亚种、、、和一种未确定的种），患病率为6.5%。分枝杆菌患病率与分析的因素之间未发现显著关联。虽然小型哺乳动物在MTC流行病学中的作用尚不能确定，但。携带的NTM可能具有致病性或干扰结核病的诊断。根据我们的结果，通过小型哺乳动物与牛之间潜在的间接接触，在野生动物-家畜界面存在NTM传播的风险。
