[一例与家族性腺瘤性息肉病相关的直肠癌异时性肝肺转移切除术后长期生存病例]
[A Case of Long-Term Survival after Resection for Metachronous Liver and Lung Metastases of Rectal Cancer Associated with Familial Adenomatous Polyposis].
作者信息
Arabiki Michiru, Kameyama Hitoshi, Abe Kaoru, Tanaka Kana, Oyanagi Hidehito, Tajima Yosuke, Nakano Mae, Nakano Masato, Shimada Yoshifumi, Ichikawa Hiroshi, Takizawa Kazuyasu, Nagahashi Masayuki, Sakata Jun, Kobayashi Takashi, Wakai Toshifumi
机构信息
Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences.
出版信息
Gan To Kagaku Ryoho. 2019 Dec;46(13):2228-2230.
A 37-year-old man was admitted to our hospital for the treatment of familial adenomatous polyposis and rectal carcinoma. He underwent total colectomy with ileoanal anastomosis(pT3N1M0, pStage Ⅲa)followed by adjuvant therapy with S-1. Three months after primary surgery, CT and MRIrevealed liver metastases(S5, S6). Laparoscopic partial hepatectomy was performed. Two years after primary surgery, new liver metastases(S2, S8)were found and we performed open partial hepatectomy and administered mFOLFOX6. Three years and 5 months after primary surgery, right lung metastases(S6, S9) were detected and the patient underwent a thoracoscopic-assisted right lung wedge resection. Repeated resection of metastases might have contributed to the long-survival in our case.
一名37岁男性因家族性腺瘤性息肉病和直肠癌入院接受治疗。他接受了全结肠切除术并进行回肠肛管吻合术（pT3N1M0，pⅢa期），随后接受S-1辅助治疗。初次手术后三个月，CT和MRI显示肝转移（S5、S6）。遂行腹腔镜下肝部分切除术。初次手术后两年，发现新的肝转移灶（S2、S8），于是我们进行了开放性肝部分切除术并给予mFOLFOX6治疗。初次手术后三年零五个月，检测到右肺转移（S6、S9），患者接受了胸腔镜辅助下右肺楔形切除术。在我们的病例中，反复切除转移灶可能有助于延长生存期。
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