Fukushima Gentaro, Ishizaki Tetsuo, Wada Akihiro, Mazaki Junichi, Enomoto Masanobu, Nagakawa Yuichi, Katsumata Kenji, Tsuchida Akihiko
Dept. of Gastrointestinal and Pediatric Surgery, Tokyo Medical University Hospital.
Gan To Kagaku Ryoho. 2019 Dec;46(13):2515-2517.
We report a case of colorectal cancer associated with Crohn's disease in a 50-year-old man. He had been diagnosed with Crohn's disease 26 years before and had undergone sigmoidectomy for sigmoid colon stenosis 19 years before. Ileal resection, was performed for ileus stenosis 12 years before. Three years before, partial resection of the small intestine was performed for perforation of the small intestine. During this period, the medical treatment was continued, but the patient experienced remission and exacerbation. He complained of anal pain at a regular outpatient visit, and endoscopic examination showed an elevated lesion immediately above the dentate line. Adenocarcinoma Group 5 was detected on biopsy. The diagnosis was rectal cancer(cT2N3M0, StageⅢb). We performed an abdominoperineal resection, a D3 lymph node dissection, and colostomy. Chemotherapy with mFOLFOX6 was provided postoperatively. The patient has survived without recurrence for 1 year and 6 months after the surgery.
我们报告一例50岁男性患有的与克罗恩病相关的结肠直肠癌。他在26年前被诊断为克罗恩病，19年前因乙状结肠狭窄接受了乙状结肠切除术。12年前因肠梗阻狭窄进行了回肠切除术。3年前因小肠穿孔进行了小肠部分切除术。在此期间，持续进行药物治疗，但患者经历了缓解和加重。他在一次定期门诊就诊时抱怨肛门疼痛，内镜检查显示齿状线正上方有一个隆起病变。活检时检测到5组腺癌。诊断为直肠癌（cT2N3M0，Ⅲb期）。我们进行了腹会阴联合切除术、D3淋巴结清扫术和结肠造口术。术后给予mFOLFOX6化疗。该患者术后已存活1年6个月，无复发。
