Service d'Anaesthésie et de Réanimation, Hôpital Nord, Aix Marseille Université, Assistance Publique Hôpitaux de Marseille, Chemin des Bourrely, 13015, Marseille, France.
Intensive Care Unit, Shaare Zedek Medical Centre and Hebrew University Faculty of Medicine, Jerusalem, Israel.
Intensive Care Med. 2020 Apr;46(4):697-713. doi: 10.1007/s00134-020-05948-0. Epub 2020 Mar 10.
Hypoxaemia is a potential life-threatening yet common complication in the peri-operative and periprocedural patient (e.g. during an invasive procedure at risk of deterioration of gas exchange, such as bronchoscopy). The European Society of Anaesthesiology (ESA) and the European Society of Intensive Care Medicine (ESICM) developed guidelines for the use of noninvasive respiratory support techniques in the hypoxaemic patient in the peri-operative and periprocedural period. The panel outlined five clinical questions regarding treatment with noninvasive respiratory support techniques [conventional oxygen therapy (COT), high flow nasal cannula, noninvasive positive pressure ventilation (NIPPV) and continuous positive airway pressure (CPAP)] for hypoxaemic patients with acute peri-operative/periprocedural respiratory failure. The goal was to assess the available literature on the various noninvasive respiratory support techniques, specifically studies that included adult participants with hypoxaemia in the peri-operative/periprocedural period. The literature search strategy was developed by a Cochrane Anaesthesia and Intensive Care trial search specialist in close collaboration with the panel members and the ESA group methodologist. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was used to assess the level of evidence and to grade recommendations. The final process was then validated by both ESA and ESICM scientific committees. Among 19 recommendations, the two grade 1B recommendations state that: in the peri-operative/periprocedural hypoxaemic patient, the use of either NIPPV or CPAP (based on local expertise) is preferred to COT for improvement of oxygenation; and that the panel suggests using NIPPV or CPAP immediately post-extubation for hypoxaemic patients at risk of developing acute respiratory failure after abdominal surgery.
低氧血症是围手术期和围手术期患者(例如,在有气体交换恶化风险的侵入性操作期间,如支气管镜检查)中潜在的危及生命但常见的并发症。欧洲麻醉学会(ESA)和欧洲重症监护医学学会(ESICM)制定了围手术期和围手术期低氧血症患者使用非侵入性呼吸支持技术的指南。专家组概述了五个关于治疗低氧血症患者的临床问题[常规氧疗(COT)、高流量鼻导管、无创正压通气(NIPPV)和持续气道正压通气(CPAP)]急性围手术期/围手术期呼吸衰竭。目的是评估各种非侵入性呼吸支持技术的现有文献,特别是包括围手术期低氧血症的成年参与者的研究。文献检索策略由 Cochrane 麻醉和重症监护试验搜索专家与专家组和 ESA 组方法学家密切合作制定。推荐评估、制定和评估(GRADE)系统用于评估证据水平并对建议进行分级。最后,该过程由 ESA 和 ESICM 科学委员会进行了验证。在 19 项建议中,有两项 1B 级建议指出:在围手术期/围手术期低氧血症患者中,与 COT 相比,使用 NIPPV 或 CPAP(基于当地专业知识)更有利于改善氧合;并且专家组建议在腹部手术后有发生急性呼吸衰竭风险的低氧血症患者拔管后立即使用 NIPPV 或 CPAP。