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综合指南传播策略对糖尿病诊断检测率的影响:一项中断时间序列研究。

Impact of a Comprehensive Guideline Dissemination Strategy on Diabetes Diagnostic Test Rates: an Interrupted Time Series.

机构信息

Diabetes Canada, Toronto, Canada.

Institute for Clinical Evaluative Sciences, Toronto, Canada.

出版信息

J Gen Intern Med. 2020 Sep;35(9):2662-2667. doi: 10.1007/s11606-020-05747-9. Epub 2020 Mar 10.

Abstract

BACKGROUND

Diabetes Canada launched a comprehensive Dissemination and Implementation (D&I) strategy to optimize uptake of their 2013 Clinical Practice Guidelines; the strategy involved continuing professional development courses, webinars, an interactive website, applications for mobile devices, point-of-care decision support tools, and media awareness campaigns. It included a focus on promoting HbA1c as the recommended diagnostic test for diabetes.

OBJECTIVE

To determine the impact of Diabetes Canada's 2013 D&I strategy on physician test-ordering behavior, specifically HbA1c testing, for the diagnosis of diabetes, using provincial healthcare administrative data.

DESIGN

Population-based interrupted time series.

SETTING

Ontario, Canada.

PARTICIPANTS

Ontario residents aged 40-79 not previously diagnosed with diabetes.

MEASUREMENTS

For each quarter between January 2005 and December 2014, we conducted an interrupted time series analysis on the first-order difference of the proportion of patients receiving HbA1c tests per quarter with an autoregressive integrated moving average model with the intervention step occurring in quarter 2 of 2013. Subgroup analyses by rurality, physician graduation year, and practice size were also conducted.

RESULTS

There were 32 quarters pre-intervention and 6 post-intervention; average sample size per quarter was 5,298,686 individuals. Pre-intervention, the quarter-to-quarter growth was 1.51 HbA1c tests per quarter per 1000 people. Post-intervention, the quarter-to-quarter growth increased by 8.45 tests per 1000 people (p < 0.005). Growth of HbA1c ordering differed significantly by region, years since physician graduation, and practice size.

LIMITATIONS

Incomplete data collection, inadequate stratification, and other unidentified confounders.

CONCLUSION

The D&I strategy resulted in a significant increase in the growth of HbA1c tests. The successful uptake of this recommendation may be due to its simplicity; guideline developers should consider this when drafting recommendations. Furthermore, differential uptake by user groups suggests that future strategies should include targeted barrier analysis and interventions to these groups.

摘要

背景

加拿大糖尿病协会推出了一项全面的传播和实施(D&I)策略,以优化其 2013 年临床实践指南的应用;该策略包括继续教育课程、网络研讨会、互动网站、移动设备应用程序、即时护理决策支持工具和媒体宣传活动。该策略还特别强调将糖化血红蛋白(HbA1c)作为诊断糖尿病的推荐检测方法。

目的

利用安大略省的医疗保健管理数据,确定加拿大糖尿病协会 2013 年 D&I 策略对医生检测开单行为(特别是 HbA1c 检测)的影响,以诊断糖尿病。

设计

基于人群的中断时间序列研究。

设置

加拿大安大略省。

参与者

年龄在 40-79 岁之间、之前未被诊断患有糖尿病的安大略省居民。

测量指标

对于 2005 年 1 月至 2014 年 12 月的每个季度,我们使用自回归积分移动平均模型对每季度接受 HbA1c 检测的患者比例进行一阶差分的中断时间序列分析,干预步骤发生在 2013 年第 2 季度。还进行了农村地区、医生毕业年份和实践规模的亚组分析。

结果

干预前有 32 个季度,干预后有 6 个季度;每个季度的平均样本量为 5298686 人。在干预前,每季度每 1000 人 HbA1c 检测量的季度增长率为 1.51 次。在干预后,每季度每 1000 人 HbA1c 检测量的季度增长率增加了 8.45 次(p<0.005)。HbA1c 检测量的增长在区域、医生毕业后年限和实践规模方面有显著差异。

局限性

数据收集不完整,分层不足和其他未识别的混杂因素。

结论

D&I 策略导致 HbA1c 检测量的显著增长。该建议的成功采用可能归因于其简单性;指南制定者在起草建议时应考虑到这一点。此外,不同用户群体的采用情况表明,未来的策略应包括针对这些群体的目标障碍分析和干预措施。

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